Now showing items 1-10 of 176
Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent L-lysine-containing domains
Myelin basic protein (MBP) is a key component of myelin, the specialized lipid membrane that encases the axons of all neurons. Both plasminogen (Pg) and tissue-type plasminogen activator (t-PA) bind to MBP with high ...
Influence of temperature on the release of plasminogen activator.
Fibrinolysis is a basic defense mechanism of the organism designed to control the deposition of fibrin in the vascular system and elsewhere. Fibrinolytic activity was measured by the fibrin plate method for three groups ...
Multiparity upregulates placental plasminogen and urokinase-type plasminogen activator
(Wiley Blackwell Publishing, Inc, 2017-04)
Problem: Multiparity increased the number of trophoblast cells in decidua of both low and high fetal loss mouse models. However, they differ in fetal survival rate and maternal thymocyte subpopulations, suggesting that ...
Reduction of Steroid-Induced Intraocular Pressure Elevation in Sheep by Tissue Plasminogen Activator
(Association For Research In Vision And Ophthalmology, 2013-12)
PURPOSE. To investigate whether tissue plasminogen activator (tPA) can prevent and/or reverse steroid-induced IOP elevation in an ovine model. METHODS. Three animal groups were subjected to bilateral steroid-induced IOP ...
The secretion of urokinase‐like plasminogen activator is inhibited by microtubule‐interacting drugs
The secretion of proteinases into the extracellular matrix is one of the main features of tumour cells, as related to their invasive behaviour. Considering the role of the microtubule cytoskeleton, and particularly the ...
Subconjunctival and topical application of recombinant tissue plasminogen activator in rabbits
Purpose: To quantify fibrin degradation products after topical and subconjunctival administration of recombinant tissue plasminogen activator in rabbits. Methods: Fibrin formation was induced in the anterior chamber in 25 ...
Peritoneal fibrinolytic activity in equines subjected to small colon enterotomy and treated with heparin
Study rationale: Heparin is routinely administered postoperatively in abdominal surgery to prevent the formation of adhesions; however, there is no consensus in the literature indicating the effectiveness of such use. ...
Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay
(Associação Brasileira de Divulgação Científica, 2004)