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Influence of pinealectomy on the amygdala kindling development in rats
(Elsevier B.V., 2006-01-09)
A considerable number of studies have demonstrated the anticonvulsant effect of melatonin. the present study examines the influence of pinealectomy on the amygdala kindling development in rats. Animals were divided into ...
Pinealectomy interferes with the circadian clock genes expression in white adipose tissue
(Wiley-Blackwell, 2015-04-01)
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24-hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression ...
Efeito neuroprotetor da melatonina e N-acetilserotonina na epileptogênese e no controle de crises em animais submetidos ao modelo da pilocarpina
(Liga Brasileira de Epilepsia (LBE), 2006-06-01)
PURPOSE: The aim of this research was to study the effects of treatment with melatonin and N-acetilserotonin in the development of pilocarpina model of epilepsy in adult male rats. METHODS: Part I - The animals were divided ...
Measurement of melatonin in body fluids: Standards, protocols and procedures
(2011-06-01)
Background and Purpose: The circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6-sulfatoxymelatonin (a6MTs) in urine, is a defining feature of suprachiasmatic nucleus (SCN) function, the ...