Buscar
Mostrando ítems 1-7 de 7
Influence of pinealectomy on the amygdala kindling development in rats
(Elsevier B.V., 2006-01-09)
A considerable number of studies have demonstrated the anticonvulsant effect of melatonin. the present study examines the influence of pinealectomy on the amygdala kindling development in rats. Animals were divided into ...
Pinealectomy interferes with the circadian clock genes expression in white adipose tissue
(Wiley-Blackwell, 2015-04-01)
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24-hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression ...
Pinealectomy-associated decrease in ribosomal gene activity in rats
(Kluwer Academic Publ, 2001-01-01)
A decrease in ribosomal gene activity is an essential feature of the aging process as it was observed in Alzheimer's disease, in elderly Down's patients and in elderly healthy people. It is well known that aging is also ...
Effect of aerobic physical exercise in pinealectomized animals submitted to the pilocarpine model of epilepsy
(Liga Brasileira de Epilepsia (LBE), 2006-06-01)
OBJECTIVE: To better clarify the positive effects of physical exercise in the epilepsy, we analyzed the effect of the pinealectomy in animals with temporal lobe epilepsy (TLE) induced by pilocarpine submitted to an aerobic ...
Rat pinealectomy: a modified direct visual approach
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2009-08-01)
PURPOSE: To report a new, direct visual approach for rat pinealectomy. METHODS: Eighty adult female rats (Rattus norvegicus albinus EPM-1 strain) were weighted and anesthetized intraperitoneally with 15 mg/kg xylazine and ...
Efeito neuroprotetor da melatonina e N-acetilserotonina na epileptogênese e no controle de crises em animais submetidos ao modelo da pilocarpina
(Liga Brasileira de Epilepsia (LBE), 2006-06-01)
PURPOSE: The aim of this research was to study the effects of treatment with melatonin and N-acetilserotonin in the development of pilocarpina model of epilepsy in adult male rats. METHODS: Part I - The animals were divided ...
Measurement of melatonin in body fluids: Standards, protocols and procedures
(2011-06-01)
Background and Purpose: The circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6-sulfatoxymelatonin (a6MTs) in urine, is a defining feature of suprachiasmatic nucleus (SCN) function, the ...