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Understanding intellectual disability through RASopathies
(Elsevier, 2014-05)
Intellectual disability, commonly known as mental retardation in the International Classification of Disease from World Health Organization, is the term that describes an intellectual and adaptive cognitive disability that ...
Phenotypic and functional evaluations of peripheral blood monocytes from chronic-form paracoccidioidomycosis patients before and after treatment
(Biomed Central Ltd, 2014-10-16)
Background: Paracoccidioidomycosis (PCM) is systemic mycosis caused by the thermal dimorphic fungus of genus Paracoccidioides, leading to either acute/subacute (AF) or chronic (CF) clinical forms. Numerous CF patients after ...
Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence
(International Society of Neuropathology, 2015-05)
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined. In this study, we established several GSC-enriched ...
Gut size flexibility in rodents: what we know, and don't know, after a century of research
(Sociedad de Biología de Chile, 2008)
Search for methylation-sensitive amplification polymorphisms in mutant figs
(2013-07-08)
Fig (Ficus carica) breeding programs that use conventional approaches to develop new cultivars are rare, owing to limited genetic variability and the difficulty in obtaining plants via gamete fusion. Cytosine methylation ...
Cytological Criteria to Predict Basal Phenotype of Breast Carcinomas
(Wiley-lissHobokenEUA, 2009)
Paternal effects associated with melanism in Harmonia axyridis (Coleoptera: Coccinellidae): mating sequence asymmetries and interactions with age-specific maternal effects
(2018-10-01)
1. For this study a cohort of melanic Harmonia axyridis males homozygous for the spectabilis allele was produced. These were used to produce four kinds of twice-mated females, comprising all four permutations of melanic ...
Risk factors for infection with coagulase-negative staphylococci in newborns from the neonatal unit of a brazilian university hospital
(Libertas Academica Ltd, 2012)
Coagulase-negative staphylococci (CoNS) are one of the most frequent causative agents of neonatal nosocomial infections, especially in premature and low-weight newborns. Risk factors for infection include extracellular ...
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency
(AMER SOC HEMATOLOGY, 2009)
Adenosine deaminase (ADA) deficiency is a disorder of the purine metabolism leading to combined immunodeficiency and systemic alterations, including skeletal abnormalities. We report that ADA deficiency in mice causes a ...