Phenothiazine derivatives are neuroleptic drugs used in the treatment of schizophrenia and anxiety. Several side effects are described for these drugs, including hepatotoxicity, which may be related to their cytotoxic ...

The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, ...

Several phenothiazines and related compounds were synthesized and their antifungal activity was evaluated in vitro. The results observed for α-chloro-N-acetyl phenothiazine led us to choose this compound as a lead in the ...

The detection of trace amounts of phenothiazines with fast, direct methods is important for medical applications and the pharmaceutical industry. In this paper we explore the concept of an electronic tongue to detect ...

The detection of trace amounts of phenothiazines with fast, direct methods is important for medical applications and the pharmaceutical industry. In this paper we explore the concept of an electronic tongue to detect ...

Microelectrode voltammetry was employed to gain information on the n-octanol/water partition ratio of phenothiazine dyes. the data were obtained as a function of pH and dye concentration in aqueous solutions. All the dyes ...

The present study shows the factors that modulate the photodamage promoted by phenothiazines. Cytochrome c was irradiated with UV light for 120 min, over a pH range from 4.0 to 8.0, in the absence and in the presence of ...