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Swimming training exacerbates pathological cardiac hypertrophy in kinin B(2) receptor-deficient mice
(Elsevier B.V., 2008-02-01)
Kallikrein-kinin system exerts cardioprotective effects against pathological hypertrophy. These effects are modulated mainly via B(2) receptor activation. Chronic physical exercise can induce physiological cardiac hypertrophy ...
Excessive training induces molecular signs of pathologic cardiac hypertrophy
(2018-11-01)
Chronic exercise induces cardiac remodeling that promotes left ventricular hypertrophy and cardiac functional improvement, which are mediated by the mammalian or the mechanistic target of rapamycin (mTOR) as well as by the ...
Pathological hypertrophy and cardiac dysfunction are linked to aberrant endogenous unsaturated fatty acid metabolism
(Public Library Science, 2018-03-01)
Pathological cardiac hypertrophy leads to derangements in lipid metabolism that may contribute to the development of cardiac dysfunction. Since previous studies, using high saturated fat diets, have yielded inconclusive ...
Masseter muscle hypertrophy - case report
(2006-12-01)
Masseter muscle hypertrophy is characterized by unilateral or bilateral enlargement of the masseter muscles affecting both males and females after puberty. Its etiology remains unknown. Limitations on mouth opening and ...
Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
(Associação Brasileira de Divulgação Científica, 2011)
Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific ...
Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts
(Elsevier B.V., 2018-11-15)
Several studies have demonstrated dysregulated cardiac microRNAs (miRNAs) following cardiac stress and development of cardiac hypertrophy and failure. miRNAs are also differentially expressed in the inflammation that occurs ...
Unraveling The Role Of High-intensity Resistance Training On Left Ventricle Proteome: Is There A Shift Towards Maladaptation?
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2016)
Unraveling The Role Of High-intensity Resistance Training On Left Ventricle Proteome: Is There A Shift Towards Maladaptation?
(Pergamon-Elsevier Science LTDOxford, 2016)
Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation
(BMC, 2014-12-24)
Background
Succinate is an intermediate of the citric acid cycle as well as an extracellular circulating molecule, whose receptor, G protein-coupled receptor-91 (GPR91), was recently identified and ...
Myosin heavy chain expression and atrophy in rat skeletal muscle during transition from cardiac hypertrophy to heart failure
(International Journal Of Experimental Pathology, 2003)
The purpose of this investigation was to determine whether changes in myosin heavy chain (MHC) expression and atrophy in rat skeletal muscle are observed during transition from cardiac hypertrophy to chronic heart failure ...