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Sexual differentiation and reproductive development of female rat offspring after paternal exposure to the anti-tumor pharmaceutical cisplatin
(2016-04-01)
Cisplatin (CP) is used to treat a number of cancers, including testicular cancer. Studies indicate that CP-treatment can impair spermatogenesis in humans and rodents by germ cell DNA binding, through different modes of ...
A deterministic worldview promotes approval of state paternalism
(Academic Press Inc., 2017)
The proper limit to paternalist regulation of citizens' private lives is a recurring theme in political theory and ethics. In the present study, we examine the role of beliefs about free will and determinism in attitudes ...
Paternal treatment with cisplatin impairs reproduction of adult male offspring in rats
(Pergamon-Elsevier B.V. Ltd, 2011-12-01)
This study evaluated the acute and persistent effects of paternal cisplatin-treatment on progeny. Wistar male rats (45 days old) were assigned into 2 groups. Control and cisplatin (CP: 1 mg/kg-d, 5 days/week, for 3 weeks, ...
Paternal treatment with cisplatin impairs reproduction of adult male offspring in rats
(Pergamon-Elsevier B.V. Ltd, 2011-12-01)
This study evaluated the acute and persistent effects of paternal cisplatin-treatment on progeny. Wistar male rats (45 days old) were assigned into 2 groups. Control and cisplatin (CP: 1 mg/kg-d, 5 days/week, for 3 weeks, ...
Paternal treatment with cisplatin impairs reproduction of adult male offspring in rats
(Pergamon-Elsevier B.V. Ltd, 2014)
Paternal treatment with cisplatin impairs reproduction of adult male offspring in rats
(Pergamon-elsevier Science LtdOxfordInglaterra, 2011)
Parental exposure to benzo(a)pyrene in the peripubertal period impacts reproductive aspects of the F1 generation in rats
(2021-03-01)
Benzo(a)pyrene (BaP) is an ubiquitous environmental pollutant which can lead to adverse effects on male reproduction. However, the persistence of these changes on a multigenerational scale has not been sufficiently explored. ...
Family dynamics. An exploration of parental sensitivity and depressive symptoms among mothers and fathers of toddlers
(SPR ITALIA, 2021)
In studies of maternal sensitivity, the influence of mothers' depressive symptomatology has been consistently highlighted. Additionally, the relevance of both maternal and paternal sensitive responses to children's development ...
Paternal selenium deficiency but not supplementation during preconception alters mammary gland development and 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rat offspring
(Wiley-Blackwell, 2016-10-15)
Breast cancer is a global public health problem and accumulating evidence indicates early-life exposures as relevant factors in the disease risk determination. Recent studies have shown that paternal nutrition can influence ...
The offspring of alcohol-exposed sires exhibit heightened ethanol intake and behavioral alterations in the elevated plus maze
(Elsevier Science Inc., 2021-05)
Research suggests that addictive traits are indeed heritable, but very few preclinical studies have explored transgenerational effects of paternal alcohol exposure. The present study addressed this gap in knowledge. We ...