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Parameters affecting cellular invasion and escape from the parasitophorous vacuole by different infective forms of Trypanosoma cruzi
(Instituto Oswaldo Cruz, Ministério da Saúde, 2003-10-01)
In this study we have examined certain aspects of the process of cell invasion and parasitophorous vacuole escape by metacyclic trypomastigotes and extracellular amastigote forms of Trypanosoma cruzi (G strain). Using Vero ...
Endocytic Rabs Are Recruited to the Trypanosoma cruzi Parasitophorous Vacuole and Contribute to the Process of Infection in Non-professional Phagocytic Cells
(Frontiers Media S.A., 2020-10)
Trypanosoma cruzi is the parasite causative of Chagas disease, a highly disseminated illness endemic in Latin-American countries. T. cruzi has a complex life cycle that involves mammalian hosts and insect vectors both of ...
The Coxiella burnetii parasitophorous vacuole
(Springer, 2012)
Abstract Coxiella burnetii is a bacterial intracellular parasite of eucaryotic cells that replicates within a membrane-bound compartment, or “parasitophorous vacuole” (PV). With the exception of human macrophages/monocytes, ...
ARF6, PI3-kinase and host cell actin cytoskeleton in Toxoplasma gondii cell invasion
(Elsevier B.V., 2009-01-16)
Toxoplasma gondii infects a variety of different cell types in a range of different hosts. Host cell invasion by T. gondii occurs by active penetration of the host cell, a process previously described as independent of ...
Trypanosoma cruzi invasion in non-phagocytic cells: an ultrastructural study
(Instituto de Histología y Embriología "Dr. Mario Burgos", 2018-12)
Trypanosoma cruzi is the causative agent of Chagas disease. This parasite requires the intracellular niche in order to proliferate and disseminate the infection. After invasion, T. cruzi resides temporarily in an acidic ...
Genetic control of natural resistance of mouse macrophages to Coxiella burnetii infection in vitro: Macrophages from restrictive strains control parasitophorous vacuole maturation
(Amer Soc Microbiology, 2004-04-01)
Macrophages from A/J and BALB/c mice were more susceptible to Coxiella burnetti phase II infection than were those from C57BL/6, C57BL/10, B10.A, C3H/HePas, and Swiss mice. Resistant macrophages effectively controlled the ...
Autophagic induction Greatly Enhances Leishmania major intracellular survival compared to Leishmania amazonensis in CBA/j-infected macrophages
(Frontiers Research Foundation, 2018-08)
CBA mouse macrophages control Leishmania major infection yet are permissive to Leishmania amazonensis. Few studies have been conducted to assess the role played by autophagy in Leishmania infection. Therefore, we assessed ...
The Diverse and Dynamic Nature of Leishmania Parasitophorous Vacuoles Studied by Multidimensional Imaging
(Public Library Science, 2012-02-01)
An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic intracellular microorganisms. We were curious to compare PV biogenesis ...
Leishmania (L.) amazonensis: Fusion between parasitophorous vacuoles in infected bone-marrow derived mouse macrophages
(Elsevier B.V., 2008-05-01)
[Leishmania (L.)] amazonensis amastigotes reside in macrophages within spacious parasitophorous vacuoles (PVs) which may contain numerous parasites. After sporadic fusion events were detected by time-lapse cinemicrography, ...