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Chlamydospore formation of paracoccidioides brasiliensis strain Pb-18
(1990-06-18)
Paracoccidioides brasiliensis is the causative agent of paracoccidioidomycosis and is known as a temperature-dependent dimorphic fungus. Even though several routes of transformation from a mycelial to yeast forms have been ...
Comparison between human and armadillo Paracoccidioides brasiliensis isolates by random amplified polymorphic DNA analysis
(Kluwer Academic Publ, 1998-01-01)
Sixty-three Paracoccidioides brasiliensis isolates obtained from three nine-banded armadillos (Dasypus novem-cinctus), one Amazonian armadillo's and 19 clinical isolates were compared by random amplified polymorphic DNA ...
Cell wall fractions from Paracoccidioides brasiliensis induce hypergammaglobulinemia
(1993-01-01)
The antibody response against the antigen sheep red blood cells (SRBC) was investigated in mice pre-treated with formalin-killed Paracoccidioides brasiliensis or with cell wall fractions of the fungus. Pre-treatment with ...
Interactions of Paracoccidioides brasiliensis with host cells: recent advances
(Springer, 2008-04-01)
Host-fungal interactions are inherently complex and dynamic. In order to identify new microbial targets and develop more effective anti-fungal therapies, it is important to understand the cellular and molecular mechanisms ...
Paracoccidioides brasiliensis: phylogenetic and ecological aspects
(Springer, 2008-04-01)
The knowledge on the biological aspects of Paracoccidioides brasiliensis has evolved greatly since the first description of the disease in 1908. From the pioneers, who were able to clearly demonstrate the fungal nature of ...
Molecular detection of Paracoccidioides brasiliensis in soil
(Taylor & Francis Ltd, 2005-12-01)
The objective of the present study was to evaluate different techniques for the detection of Paracoccidioides brasiliensis in soil, e.g., culture, animal inoculation and specific DNA amplification by Nested PCR. We designed ...
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients
(Instituto Oswaldo Cruz, Ministério da Saúde, 2006-05-01)
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different ...
Molecular approaches for eco-epidemiological studies of Paracoccidioides brasiliensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2009-07-01)
Medical mycology has greatly benefited from the introduction of molecular techniques. New knowledge on molecular genetics has provided both theoretical and practical frameworks, permitting important advances in our ...
Involvement of the major glycoprotein (gp43) of Paracoccidioides brasiliensis in attachment to macrophages
(1998-12-01)
The yeast form of Paracoccidioides brasiliensis, the causative agent of a deep mycosis in humans, is known to be phagocytized by, and to multiply inside, macrophages. In this work we describe the involvement of gp43, a ...
Antibody response to the 43 kDa glycoprotein of Paracoccidioides brasiliensis as a marker for the evaluation of patients under treatment
(1990-09-14)
Sera of patients with paracoccidioidomycosis contained IgG-, IgA-, and IgM-specific antibodies to a 43 kDa antigen contained in the filtrate of a culture of Paracoccidioides brasiliensis. IgG- and IgA-specific antibodies ...