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Pamidronate for the treatment of osteoporosis secondary to chronic cholestatic liver disease in Wistar rats
(Associação Brasileira de Divulgação Científica, 2012)
Osteoporosis is a major complication of chronic cholestatic liver disease (CCLD). We evaluated the efficacy of using disodium pamidronate (1.0 mg/kg body weight) for the prevention (Pr) or treatment (Tr) of cholestasis-induced ...
Pamidronate Attenuates Oxidative Stress and Energetic Metabolism Changes but Worsens Functional Outcomes in Acute Doxorubicin-Induced Cardiotoxicity in Rats
(2016-12-01)
Background: Cardiotoxicity is the major side effect of doxorubicin. As mechanisms that are involved in cardiotoxicity are ambiguous, new methods for attenuating cardiotoxicity are needed. Recent studies have shown that ...
Long-term pamidronate treatment of polyostotic fibrous dysplasia of bone: A case series in young adults
(Elsevier, 2009-04)
Background: Limited information is available about long-term pamidronate treatment in adults with fibrous dysplasia (FD) of bone. Objective: The aim of this case series was to report the clinical outcomes and the biochemical ...
Long-term control of hypercalcaemia in an infant with Williams-Beuren syndrome after a single infusion of biphosphonate (Pamidronate)
(Wiley Blackwell Publishing, Inc, 2004-07)
Aim: To report the efficacy of Pamidronate to treat hypercalcaemia in a patient with Williams-Beuren syndrome (WBS). Results: We report a 14-mo-old male infant presenting hypercalcaemia, elfin face and other dysmorphological ...
Pamidronate attenuates diastolic dysfunction induced by myocardial infarction associated with changes in geometric patterning
(Karger, 2015-01-01)
Background/Aims: The aim of this study was to evaluate the influence of pamidronate on ventricular remodeling after myocardial infarction. Methods: Male Wistar rats were assigned to four groups: a sham group, in which ...
Effects of Pamidronate in Acute Cardiotoxicity Induced by Doxorubicin in Rats
(Federation Amer Soc Exp Biol, 2015-04-01)
Safety and efficacy of a 1-year treatment with zoledronic acid compared with pamidronate in children with osteogenesis imperfecta
(Walter de Gruyter & Co, 2012-06-01)
Pamidronate (PAM) infusion is the standard treatment in children with osteogenesis imperfecta (OI). Zoledronic acid (ZOL) is a bisphosphonate with higher potency and faster intravenous infusion, but its efficacy and safety ...
A Role of Oral Bacteria in Bisphosphonate-induced Osteonecrosis of the Jaw
(Sage Publications Inc, 2011-11-01)
No consensus has yet been reached to associate oral bacteria conclusively with the etio-pathogenesis of bisphosphonate-induced osteonecrosis of the jaw (BONJ). Therefore, the present study examined the effects of oral ...
A Role of Oral Bacteria in Bisphosphonate-induced Osteonecrosis of the Jaw
(Sage Publications Inc, 2011-11-01)
No consensus has yet been reached to associate oral bacteria conclusively with the etio-pathogenesis of bisphosphonate-induced osteonecrosis of the jaw (BONJ). Therefore, the present study examined the effects of oral ...