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Imaging amyloid precursor protein in vivo: An axonal transport assay
(Humana Press, 2012-08)
Fusion of fluorescent probes to axonally transported proteins represents an established approach that enables live imaging of axonal transport. In this approach, in vivo examination of fluorescent particle dynamics provides ...
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
(2015)
Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine receptor (RyR) Ca2+ release channels. Sub-micromolar ryanodine concentrations activate RyR channels while micromolar ...
Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death
(1999)
The key target of this study was the tau protein kinase II system (TPK II) involving the catalytic subunit cdk5 and the regulatory component p35. TPK II is one of the tau phosphorylating systems in neuronal cells, thus ...
Serotype b of Aggregatibacter actinomycetemcomitans triggers pro-inflammatory responses and amyloid beta secretion in hippocampal cells: a novel link between periodontitis and Alzheimer ' s disease?
(2019)
Introduction: Previous reports have proposed that Periodontal disease (PDis) predisposes to Alzheimer's disease (AD), both highly prevalent pathologies among the elderly. The bacteria Aggregatibacter actinomycetemcomitans ...
Protocol for evaluating neuronal polarity in murine models
(Cell Press, 2020-12)
The establishment of polarity is crucial for the physiology and wiring of neurons. Therefore, monitoring the axo-dendritic specification allows the mechanisms and signals associated with development, growth, and disease ...
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
(Academic Press Inc., 2015)
© 2015 Elsevier Inc. All rights reserved. Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine receptor (RyR) Ca2+ release channels. Sub-micromolar ryanodine concentrations ...
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2þ release without affecting endoplasmic reticulum Ca2þ content in primary hippocampal neurons
(Elsevier, 2015)
Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine
receptor (RyR) Ca2þ release channels. Sub-micromolar ryanodine concentrations activate RyR channels
while micromolar ...
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
(Academic Press, 2015)
Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine
receptor (RyR) Ca2þ release channels. Sub-micromolar ryanodine concentrations activate RyR channels
while micromolar ...
Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons
(John Wiley and Sons Inc., 2014)
Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...