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PPAR beta/delta and PPAR gamma maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone
(Frontiers Research Foundation, 2015)
The subventricular zone(SVZ)is one of the main niches of neural stem cells in the adult mammalian brain.
PPAR beta/delta and PPAR gamma maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone
(Frontiers Research Foundation, 2015)
The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis and oligodendrogesis, mainly in the olfactory ...
Molecular properties of fatty acids related to PPAR binding and metabolic diseases
(SpringerBasel, 2013-07)
Peroxisome proliferator-activated receptor (PPAR) is a class of nuclear receptors responsible for the transcription of genes that regulate the metabolism of carbohydrates and lipids. The main endogenous ligands of PPARs ...
New PPAR alpha/gamma/delta Optimal Activator Rationally Designed by Computational Methods
(Soc Brasileira Quimica, 2016-09-01)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that acts as a transcription factor, regulating glucose, lipid and inflammation signaling and it is exploited in type 2 diabetes ...
Effects of 15-deoxy-Delta(12, 14) prostaglandin J(2) and ciglitazone on human cancer cell cycle progression and death: The role of PPAR gamma
(ELSEVIER SCIENCE BV, 2008)
The role of PPAR-gamma in ciglitazone and 15-d PGJ(2)-induced apoptosis and cell cycle arrest of Jurkat (before and after PPAR gamma gene silencing), U937 (express high levels of PPAR gamma) and HeLa (that express very low ...
Activation of PPAR alfa and PPAR beta/delta regulates Sertoli cell metabolism.
(Elsevier Ireland, 2014-01)
The purpose of this study was to evaluate the existence of a possible simultaneous regulation of fatty acid (FA) metabolism and lactate production by PPAR a and PPAR b/d activation in Sertoli cells (SC). SC cultures obtained ...
Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) gamma Activators and Pan-PPAR Partial Agonists
(Public Library Science, 2012-05-23)
Thiazolidinediones (TZDs) act through peroxisome proliferator activated receptor (PPAR) gamma to increase insulin sensitivity in type 2 diabetes (T2DM), but deleterious effects of these ligands mean that selective modulators ...