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Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta
(W B SAUNDERS CO LTD, 2008-08)
It is known that human syncytiotrophoblast (hSCT) actively transports more than 80% of the Ca2þ that goes from maternal to fetal circulation.
Transepithelial transport of Ca2þ is carried out through channels, transporters ...
PMCA activity and membrane tubulin affect deformability of erythrocytes from normal and hypertensive human subjects
(Elsevier Science, 2015-11)
Our previous studies demonstrated formation of a complex between acetylated tubulin and brain plasma membrane Ca2 +-ATPase (PMCA), and the effect of the lipid environment on structure of this complex and on PMCA activity. ...
Diacylglycerol regulates the plasma membrane calcium pump from human erythrocytes by direct interaction
(Archives of Biochemistry and Biophysics, 2013)
Influencia del entorno lipídico sobre la actividad biológica de la bomba de calcio de Membrana plasmática
(2017-06-01)
Las proteínas de membrana son esenciales para la regulación de la composición del medio celular, el potencial de membrana, el metabolismo y las vías de señalización. Por su ubicación son consideradas la puerta de ingreso ...
The Effect of Ethanol on the Plasma Membrane Calcium Pump Is Isoform-specific
(THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2017)
Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection
(Public Library Science, 2012-05-23)
Aspergillus fumigatus is a primary and opportunistic pathogen, as well as a major allergen, of mammals. The Ca+2-calcineurin pathway affects virulence, morphogenesis and antifungal drug action in A. fumigatus. Here, we ...
Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection
(Public Library Science, 2012-05-23)
Aspergillus fumigatus is a primary and opportunistic pathogen, as well as a major allergen, of mammals. The Ca+2-calcineurin pathway affects virulence, morphogenesis and antifungal drug action in A. fumigatus. Here, we ...
Plasma membrane calcium ATPase activity is regulated by actin oligomers through direct interaction
(American Society for Biochemistry and Molecular Biology, 2013-08)
As recently described by our group, plasma membrane calcium ATPase (PMCA) activity can be regulated by the actin cytoskeleton. In this study, we characterize the interaction of purified G-actin with isolated PMCA and examine ...
Differential Effects of G- and F-Actin on the Plasma Membrane Calcium Pump Activity
(Humana Press, 2012-11)
We have previously shown that plasma membrane calcium ATPase (PMCA) pump activity is affected by the membrane protein concentration (Vanagas et al., Biochim Biophys Acta 1768:1641-1644, 2007). The results of this study ...
Expressão de proteínas envolvidas no transporte transepitelial de cálcio na próstata de ratos em envelhecimento
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE MORFOLOGIAPrograma de Pós-Graduação em Biologia CelularUFMG, 2020-02-19)
Calcium is a second messenger crucial for the execution of diverse cellular functions, including cell proliferation, survival and death. Its transport across epithelia is performed in three steps through the action of ...