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Proinflammatory response of human osteoblastic cell lines and Osteoblast-monocyte interaction upon infection with Brucella spp
(American Society for Microbiology, 2009-03)
The ability of Brucella spp. to infect human osteoblasts and the cytokine response of these cells to infection were investigated in vitro. Brucella abortus, B. suis, B. melitensis, and B. canis were able to infect the ...
B. Abortus Modulates Osteoblast Function Through the Induction of Autophagy
(Frontiers Media SA, 2018-12)
Osteoarticular brucellosis is the most common localization of human active disease. Osteoblasts are specialized mesenchymal-derived cells involved in bone formation and are considered as professional mineralizing cells. ...
Purinergic (ATP) signaling stimulates JNK1 but not JNK2 MAPK in osteoblast-like cells: Contribution of intracellular Ca2+ release, stress activated and L-voltage-dependent calcium influx, PKC and Src kinases
(Elsevier Science Inc, 2008-09-15)
This work shows that ATP activates JNK1, but not JNK2, in rat osteoblasts and ROS-A 17/2.8 osteoblast-like cells. In ROS-A 17/2.8 cells ATP induced JNK1 phosphorylation in a dose- and time-dependent manner. JNK1 phosphorylation ...
Brucella abortus invasion of osteoblasts inhibits bone formation
(American Society for Microbiology, 2012-06-12)
Osteoarticular brucellosis is the most common presentation of the active disease in humans. Loss of bone is a serious complication of localized bacterial infection of bones or the adjacent tissue, and brucellosis proved ...
Controlled adhesion and proliferation of a human osteoblastic cell line by tuning the nanoporosity of titania and silica coatings
(Royal Society of Chemistry, 2013-02)
The engineering of surfaces to control cell adhesion represents an active area of biomaterials research. Herein, we demonstrate that it is possible to tune the adhesion and proliferation of a human osteoblastic cell line ...
Involvement of GSK3/β-catenin in the action of extracellular ATP on differentiation of primary cultures from rat calvaria into osteoblasts
(Wiley-liss, div John Wiley & Sons Inc., 2018-06-22)
Modulation of purinergic receptors play an important role in the regulation of osteoblasts differentiation and bone formation. In this study, we investigated the involvement of the GSK3/βcatenin signaling in the action of ...
Aqueous extract from Opuntia megapotamica fruit pulp promotes osteoblast activity
(Peertechz Publications, 2020-05-20)
Objetive: Osteoporosis and osteopenia are age-related chronic diseases with increased morbidity rates among postmenopausal women. Natural productsinvestigation for prevention and treatment of these conditions is growing, ...
Biological effects of a complex of vanadium(V) with salicylaldehyde semicarbazone in osteoblasts in culture: Mechanism of action
(Elsevier Science Inc, 2009-04-01)
Vanadium compounds display important pharmacological actions in vivo and in vitro systems. Semicarbazones are versatile ligands with therapeutic effects. Herein, we report the effects of VVO2(salicylaldehydesemicarbazone) ...
Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture
(Bentham Science Publishers, 2010-04)
Strong chelating ligands as oxodiacetate (oda) are model systems to study the process of metal trapping by livingorganisms. Vanadium compounds display interesting biological and pharmacological actions. In vertebrates, ...