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Dependência de opioide em pacientes com dor crônica
(Sociedade Brasileira para o Estudo da Dor, 2011-06-01)
BACKGROUND AND OBJECTIVES: Although opioids are useful to treat chronic non-oncologic pain, there are caveats, especially due to abuse and dependence. This study aimed at reviewing the use of opioids in chronic non-oncologic ...
Uso e rotação de opioides para dor crônica não oncológica
(Sociedade Brasileira de Anestesiologia, 2012-08-01)
BACKGROUND AND OBJECTIVES: Prolonged use of opioids is a possibility for chronic pain treatment. Opioids are effective for virtually all chronic non-cancer pain syndromes, but may cause dependence. The aim of this paper ...
The 'fentanyl epidemic' in Canada - Some cautionary observations focusing on opioid-related mortality
(Academic Press Inc Elsevier Science, 2018)
In Canada, opioid-related overdose mortality has steeply increased in recent years
Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
(Sociedade Brasileira para o Estudo da Dor, 2014-12-01)
BACKGROUND AND OBJECTIVES: Opioid-induced hyperalgesia is a topic not yet fully understood in terms of mechanisms, diagnosis, prevention and treatment. Thus, it seems of great importance to evaluate this phenomenon that ...
Differential effects of exercise on brain opioid receptor binding and activation in rats
(Wiley-Blackwell, 2015-01-01)
Physical exercise stimulates the release of endogenous opioid peptides supposed to be responsible for changes in mood, anxiety, and performance. Exercise alters sensitivity to these effects that modify the efficacy at the ...
PARTICIPATION OF OPIOID RECEPTORS IN THE MODULATION OF THE ANALGESIC RESPONSE BY ADRENAL AND GONADAL GLANDS
(Associação Brasileira de Divulgação Científica (ABRADIC), 1991-01-01)
The involvement of opioid receptors in the analgesic response was evaluated by the tail-immersion test in simultaneously adrenalectomized and ovariectomized female Wistar rats (210-250 g). The reaction time (mean +/- SEM) ...
ADMINISTRAÇÃO EPIDURAL DE OPIÓIDES em CÃES
(Universidade Federal de Santa Maria (UFSM), 2002-04-01)
Os opióides têm sido utilizados em Medicina Veterinária há vários anos como alternativa para o alívio da dor pós-operatória ou traumática. Atualmente, tem-se dado maior valor ao controle da dor nos animais, visando a ...
Associacao de opioides lipofilicos a bupivacaina na anestesia peridural. Ha vantagem no aumento da dose do opioide?
(1998-11-30)
Background and Objectives: - The effects of associating lipophilic opioids to local anesthetics in epidural anesthesia are not well defined. There are still questions and controversies about opioid doses to be used and ...
Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors
(Elsevier B.V., 2007-03-28)
Previous studies have established a relationship between sleep disruption and pain, and it has been suggested that hyperalgesia induced by paradoxical sleep deprivation (PSD) could be due to a reduction of opioidergic-ne ...