Search
Now showing items 1-10 of 482
Analysis of the opioid-opioid combinations according to the nociceptive stimulus in mice
(2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine, when two of them were systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid ...
Spread the Word: There Are Two Opioid Crises!
(2020-08-01)
Pain is associated with emotional and physical suffering that severely impacts quality of life. Many guidelines for the treatment of moderate to severe cancer pain indicate the use of opioids. For a small proportion of the ...
Opioides, sexo e gênero
(Sociedade Brasileira para o Estudo da Dor, 2011)
JUSTIFICATIVA E OBJETIVOS: Sexo é um fator importante na modulação da experiência dolorosa. Evidências significativas têm demonstrado que a experiência à dor difere entre homens e mulheres, bem como na resposta à ativação ...
Antinociception induced by acute oral administration of sweet substance in young and adult rodents: The role of endogenous opioid peptides chemical mediators and mu(1)-opioid receptors
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
The present work aimed to investigate the effects of acute sucrose treatment on the perception of painful stimuli. Specifically, we sought to determine the involvement of the endogenous opioid peptide-mediated system as ...
Cognitive impairment in cancer pain patients receiving opioids
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
This study aimed to compare cognitive function of cancer pain patients being given opioids during their cancer treatment (n = 14) with that of patients receiving treatment without opioids (n = 12). Correlations between ...
Activation of μ opioid receptors in the LPBN facilitates sodium intake in rats
(2015)
Important inhibitory mechanisms for the control of water and sodium intake are present in the lateral parabrachial nucleus (LPBN). Opioid receptors are expressed by LPBN neurons and injections of endorphin (nonspecific ...
mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat
(Blackwell Publishing LtdOxfordInglaterra, 2002)
Prescription of opioids at the moment of discharge from an emergency department Prescripción de opioides al alta de un servicio de urgencia
(Sociedad Medica de Santiago, 2017)
© 2017, Sociedad Medica de Santiago. All rights reserved. Background: There is a worrisome increase in opioid prescription worldwide. Their use and overuse may cause adverse outcomes. Aim: To determine incidence and ...
Racemic salsolinol and its enantiomers act as agonists of the µ-opioid receptor by activating the Gi protein-adenylate cyclase pathway
(Frontiers Media S.A., 2017)
© 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...