Buscar
Mostrando ítems 1-10 de 89
Analysis of the opioid–opioid combinations according to the nociceptive stimulus in mice
(ELSEVIER, 2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and
morphine,whentwoofthemwere systemically combined in a 1:1 potency ratio, in the hot plate, the acetic
acid writhing, ...
Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain
(BioMed Central, 2014)
Background: Opioids have been used for the management of pain and coadministration of two opioids may
induce synergism. In a model of tonic pain, the acetic acid writhing test and in a phasic model, the hot plate, ...
The effect of opioid antagonists on synergism between dexketoprofen and tramadol
(2009)
The antinociceptive activity of dexketoprofen was studied in mice using the formalin assay for orofacial pain. The interaction between dexketoprofen and co-administered tramadol was studied using isobolographic analysis. ...
Prescripción de opioides al alta de un servicio de urgencia
(Sociedad Médica Santiago, 2017)
Background: There is a worrisome increase in opioid prescription worldwide.
Their use and overuse may cause adverse outcomes. Aim: To determine
incidence and characteristics of opioid prescription at discharge at an ...
Cross-tolerance to acute administration of mu and kappa opioid agonists at the spinal cord level in the rat
(1996)
Development of tolerance and cross-tolerance after acute administration of the μ agonist morphine and the K agonist U-50,488H was assessed in rats, through recording of a C-fiber-evoked spinal nociceptive reflex. Rats ...
¿Qué saben los pacientes con dolor crónico no oncológico sobre los opioides que les formulan?
(Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud, 2016-06-01)
Usos terapéuticos potenciales de los antagonistas opioides: Fisiopatología y evidencia preclínica
(Universidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Farmacia, 2015-09-01)
El sistema opioide, del cual forman parte los péptidos opioides endógenos y sus receptores (Miu, Kappa, delta y ORL), tiene un papel importante en la fisiología de diferentes sistemas. Existe una creciente evidencia de su ...
κ Opioid receptor-mediated depression of activity evoked in convergent dorsal horn cells by thermal and non-thermal noxious stimulation
(1990)
The response of convergent dorsal horn cells to tonic and phasic noxiuos heating and to noxious pinching was studied and after topical application of a solution (30 nmol) of the κ agonist U-50,488H to the dorsal surface ...
Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
(Frontiers Media, 2020)
The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons. Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive-compulsive disorder. Compulsive behavior is a feature ...
Tratamiento farmacológico del dolor en pacientes con cáncer.
(2013-09-20)
La Organización Mundial de la Salud define el cuidado paliativo como el cuidado total y activo en aquellos pacientes que no
responden a un tratamiento curativo. El control del dolor, otros síntomas y los problemas ...