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Preventive effect of the bark of Passiflora edulis on obesity-related disorders and oxidative stress in db/db mice
(2019-07-01)
Purpose: To verify if the bark of Passiflora edulis prevents obesity-related disorders and oxidative stress in db/db mice. Methods: Obese male db/db mice (n = 14 animals) were randomly divided into two groups to receive ...
Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight
(Springer, 2012-08-01)
Previous studies showed that leptin-deficient (ob/ob) mice develop obesity and impaired ventilatory responses to CO2 . In this study, we examined if leptin replacement improves chemorespiratory responses to hypercapnia (7 ...
Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
(2011)
Background & Aims: Metabolic syndrome is secondary to obesity and characterized by dyslipidemia, insulin resistance, and hypertension. Non-alcoholic fatty liver disease is its hepatic manifestation, whose progression-limiting ...
Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
(2011)
Background & Aims: Metabolic syndrome is secondary to obesity and characterized by dyslipidemia, insulin resistance, and hypertension. Non-alcoholic fatty liver disease is its hepatic manifestation, whose progression-limiting ...
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice
(Public Library of ScienceSan Francisco, 2013-10-24)
A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of ...