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Clinical pharmacology of nicotine in electronic nicotine delivery systems
(2019)
Electronic nicotine delivery systems (ENDS) are a heterogeneous class of products in which an electrically powered coil is used to heat a liquid matrix, or e-liquid, that contains nicotine, solvents (e.g. propylene glycol, ...
Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats
(2020)
Background: Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the setting ...
Sensitization-dependent nicotine place preference in the adult zebrafish
(Pergamon-Elsevier Science Ltd, 2019-06)
Sensitization of motor activity is a behavioural test to evaluate the effects of psychostimulants. Conditioned place preference (CPP) is an associative learning procedure to examine the rewarding properties of drugs. We ...
Influence of nicotine and cotinine impregnation on the first step of periodontal regeneration: clot stabilization
(2013)
This study analyzes the clot stabilization on root surfaces of teeth impregnated with cotinine and nicotine and the influence of the scaling in the adhesion of blood components, observing the influence of new exposition ...
Administration of N-acetylcysteine plus acetylsalicylic acid markedly inhibits nicotine reinstatement following chronic oral nicotine intake in female rats
(Frontiers Media, 2021)
Background
Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the ...
Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking
(Soc Neuroscience, 2015-04-15)
Alcohol and nicotine are the two most co-abused drugs in the world. Previous studies have shown that nicotine can increase alcohol drinking in nondependent rats, yet it is unknown whether nicotine facilitates the transition ...
Acute behavioural responses to nicotine and nicotine withdrawal syndrome are modified in GABAB1 knockout mice
(Pergamon-Elsevier Science Ltd, 2012-10)
Nicotine is the main active component of tobacco, and has both acute and chronic pharmacological effects that can contribute to its abuse potential in humans. The aim of the present study was to evaluate a possible role ...
Nicotine withdrawal hyperalgesia and opioid-mediated analgesia depend on nicotine receptors in nucleus accumbens
(Pergamon-elsevier Science LtdOxfordInglaterra, 2001)
Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations
(Springer, 2014-08)
Rationale:Nicotine is a major active ingredient in tobacco and plays a major role in tobacco addiction. In rodents, repeated nicotine administration produces behavioral responses related to its addictive properties, such ...