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Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells
(Elsevier B.V., 2017)
© 2016 Elsevier B.V. Duchenne muscular dystrophy (DMD) is a neuromuscular disease originated by mutations in the dystrophin gene. A promising therapeutic approach deals with functional substitution of dystrophin by utrophin, ...
Novel therapies targeting cardioprotection and regeneration
(Bentham Science Publishers, 2017)
Cardiovascular disease is the leading cause of death worldwide. The heart is susceptible to pathologies that impact the myocardium directly, such as myocardial infarction and consequent heart failure, as well as conditions ...
Electrical stimulation induces calcium-dependent up-regulation of neuregulin-1β in dystrophic skeletal muscle cell lines
(2012)
Duchenne muscular dystrophy (DMD) is a
neuromuscular disease originated by reduced or no
expression of dystrophin, a cytoskeletal protein that
provides structural integrity to muscle fibres. A
promising pharmacological ...