Now showing items 1-10 of 18
NEUREGULINS 1-ALPHA AND 1-BETA ON THE REGENERATION THE PERIPHERAL NERVES
(ATHA COMUNICACAO & EDITORA, 2010)
Objective: To evaluate the effect of the neuregulins 1-alpha and 1-beta on the regeneration the sciatic nerves of male adult C57BL/6J mice, using the tubulization technique. Methods: Eighteen animals were used, divided ...
The role of the Neuregulin-1/Erbb signaling pathway in cardiac morphogenesis and remodeling
(Sociedad Argentina de Fisiología, 2014-02)
Neuregulin-1 (NRG1) signaling through tyrosine kinase receptors erbB2 and erbB4 was revealed essential for cardiac development as mouse mutated in the Nrg1 or either cognate receptors Erbb2 or Erbb4 genes lack the formation ...
Neuregulin-1/erbB activities with focus on the susceptibility of the heart to anthracyclines
(Baishideng Publishing Group, 2014-07)
Neuregulin-1 (NRG1) signaling through the tyrosine kinase receptors erbB2 and erbB4 is required for cardiac morphogenesis, and it plays an essential role in maintaining the myocardial architecture during adulthood. The ...
Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells
(Elsevier B.V., 2017)
© 2016 Elsevier B.V. Duchenne muscular dystrophy (DMD) is a neuromuscular disease originated by mutations in the dystrophin gene. A promising therapeutic approach deals with functional substitution of dystrophin by utrophin, ...
Neuregulinas 1-alfa e 1-beta na regeneração de nervos periféricos
(Atha Comunicação & Editora, 2010)
OBJETIVO: Avaliar o efeito das neuregulinas 1-alfa e 1-beta na regeneração de nervos ciáticos de camundongos C57BL/6J, adultos, machos, através da técnica de tubulização. MÉTODOS: Utilizaram-se 18 animais, divididos em 3 ...
Novel therapies targeting cardioprotection and regeneration
(Bentham Science Publishers, 2017)
Cardiovascular disease is the leading cause of death worldwide. The heart is susceptible to pathologies that impact the myocardium directly, such as myocardial infarction and consequent heart failure, as well as conditions ...