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Neprilysin: A Potential Therapeutic Target of Arterial Hypertension?
(Bentham Science Publishers, 2020)
Arterial hypertension is the most prevalent chronic disease in the adult population of developed countries and it constitutes a significant risk factor in the development of cardiovascular disease, contributing to the ...
Neprilysin carboxydipeptidase specificity studies and improvement in its detection with fluorescence energy transfer peptides
(Walter de Gruyter & Co, 2007-04-01)
We examined the substrate specificity of the carboxydipeptidase activity of neprilysin (NEP) using fluorescence resonance energy transfer (FRET) peptides containing ortho-aminobenzoyl (Abz) and 2,4-dinitrophenyl (Dnp) as ...
Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases
(Associação Brasileira de Divulgação Científica, 1997-10-01)
Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-<!-- $MVD$:face(Times) ...
Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in mice
(Wiley-blackwellMaldenEUA, 2008)
[des-arg(1)]-proctolin: A Novel Nep-like Enzyme Inhibitor Identified In Tityus Serrulatus Venom
(Elsevier Science INCNew York, 2016)
[des-arg(1)]-proctolin: A Novel Nep-like Enzyme Inhibitor Identified In Tityus Serrulatus Venom
(ELSEVIER SCIENCE INCNEW YORK, 2016)
Effects of experimental intracerebral ventricular injection of amyloid beta peptide (1-42) aggregates on daily rhythms of Aβ-degrading enzymes in the hippocampus: Relevance to Alzheimer's disease pathophysiology
(Elsevier, 2019-09)
One of the main pathological features in the Alzheimer disease (AD) is the presence of senile plaques, primarily composed of Aβ peptide aggregates, in cortex and hippocampus. AD late onset, which constitutes 90% of cases, ...