Now showing items 1-10 of 268
Development of stained polymeric nanocapsules loaded with model drugs: Use of a fluorescent poly(phenyleneethynylene)
(Elsevier B.V., 2016-11-01)
A phenyleneethynylene polymer (here denoted pPy3E-sqS) was synthesized and characterized by UV-vis spectroscopy, fluorescence spectroscopy, and TEM, and was used for the staining of polymeric nanocapsules. The nanocapsules ...
Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities
This paper describes a comparison of different polymeric nanocapsules (NCs) prepared with the polymers poly(d,l-lactide-co-glycolide), poly(l-lactide) (PLA), and poly(e-caprolactone) and used as carrier systems for the ...
Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery
Here we report the development of new drug nanocarriers – named hyaluronan nanocapsules – for the intracellular delivery of hydrophobic anticancer drugs. These nanocapsules are composed of a lipid core and a shell of ...
Benzocaine loaded biodegradable poly-(D,L-lactide-co-glycolide) nanocapsules: factorial design and characterization
(Elsevier B.V., 2009-12-15)
Local anesthetics are able to induce pain relief since they bind to the sodium channel of excitable membranes, blocking the influx of sodium ions and the propagation of the nervous impulse. Benzocaine (BZC) is a local ...
Mucoadhesive Amphiphilic Methacrylic Copolymer-Functionalized Poly(epsilon-caprolactone) Nanocapsules for Nose-to-Brain Delivery of Olanzapine
(Amer Scientific Publishers, 2015-08-01)
Nose-to-brain drug delivery has been proposed to overcome the low absorption of drugs in central nervous system due to the absence of brain-blood barrier in the olfactory nerve pathway. However, the presence of a mucus ...
Incorporation of Magnetic Nanoparticles in Poly(Methyl Methacrylate) Nanocapsules
(Wiley VCH Verlag, 2017-03)
Magnetic nanoparticles (MNPs) encapsulated in polymeric systems are promising materials for hyperthermia treatments and targeting drug delivery in cancer therapy. To improve the encapsulation efficiency of therapeutic ...
Development Of Stained Polymeric Nanocapsules Loaded With Model Drugs: Use Of A Fluorescent Poly(phenyleneethynylene)
(Elsevier Science BVAmsterdam, 2016)
NANOPARTÍCULAS CONTENDO PROPIONATO DE CLOBETASOL: PREPARAÇÃO, CARACTERIZAÇÃO E INCORPORAÇÃO EM HIDROGÉIS
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol propionate in nanocapsule suspensions. ...