Buscar
Mostrando ítems 1-10 de 2007
New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine
(Springer New York LLC, 2014)
Clinical pharmacology of nicotine in electronic nicotine delivery systems
(2019)
Electronic nicotine delivery systems (ENDS) are a heterogeneous class of products in which an electrically powered coil is used to heat a liquid matrix, or e-liquid, that contains nicotine, solvents (e.g. propylene glycol, ...
Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-01-01)
Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral ...
Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish
(Public Library of Science, 2013-07)
Studies using mice and rats have demonstrated that nicotine induces a conditioned place preference (CPP), with more effective results obtained by using biased procedures. Zebrafish have also been used as a model system to ...
Pre-exposure to nicotine with nocturnal abstinence induces epigenetic changes that potentiate nicotine preference
(Humana Press, 2019-12)
Prior exposure to drugs of abuse may facilitate addiction. It has been described that pre-exposure to nicotine can increase or, contrarily, prevent conditioned place preference (CPP). Here, we evaluated the effect of ...
Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats
(2020)
Background: Nicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the setting ...
Influence of nicotine and cotinine impregnation on the first step of periodontal regeneration: clot stabilization
(2013)
This study analyzes the clot stabilization on root surfaces of teeth impregnated with cotinine and nicotine and the influence of the scaling in the adhesion of blood components, observing the influence of new exposition ...