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To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?
(Sociedad de Biología de Chile, 2004)
NAADP-sensitive two-pore channels are present and functional in gastric smooth muscle cells
(Churchill Livingstone, 2014-08-01)
Nicotinic acid adenine dinucleotide phosphate (NAADP) has been identified as an important modulator of Ca2+ release from the endo-lysosomal system in a variety of cells by a new and ubiquitous class of endo-lysosomal ion ...
Glutamate induces autophagy via the two-pore channels in neural cells
(Impact Journals Llc, 2017)
NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2. However, the activities ...
Estudo da sinalização de Ca2+ na modulação e agregação da proteína huntingtina mutante em modelo celular da doença de Huntington
(Universidade Federal de São Paulo, 2022-05-23)
A doença de Huntington (DH) é uma doença neurodegenerativa causada por uma mutação no gene responsável pela codificação da proteína huntingtina (Htt), que resulta na formação da huntingtina mutante (mHtt). Essa proteína ...
Aproximación a la regulación de algunas enzimas involucradas en el metabolismo del NAD+ en Giardia duodenalis
(Bogotá - Ciencias - Maestría en Ciencias - BioquímicaDepartamento de QuímicaUniversidad Nacional de Colombia - Sede Bogotá, 2019-04-22)
Giardia duodenalis is a parasite that causes giardiasis. This affects humans and mammals, and it is currently considerated a public health problem. G. duodenalis is a high relevance organism due to its basal evolution and ...