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Visualization of fast calcium oscillations in the parafascicular nucleus
(Springer, 2013-04)
The parafascicular nucleus (Pf) is an ascending target of the pedunculopontine nucleus (PPN) and is part of the “non-specific” intralaminar thalamus. The PPN, part of the reticular activating system, is mainly involved in ...
High-Threshold Ca2+ channels behind gamma band activity in the pedunculopontine nucleus (PPN)
(American Physiological Society and The Physiological Society, 2015-07)
The pedunculopontine nucleus (PPN) is part of the Reticular Activating System, and active during waking and REM sleep. Previous results showed that all PPN cells plateau at gamma frequencies and intrinsic membrane oscillations ...
Pedunculopontine arousal system physiology – implications for insomnia
(Elsevier Science, 2015-04)
We consider insomnia a disorder of waking rather than a disorder of sleep. This review examines the role of the reticular activating system, especially the pedunculopontine nucleus, in the symptoms of insomnia, mainly ...
Spatiotemporal properties of high-speed calcium oscillations in the pedunculopontine nucleus
(American Physiological Society, 2013)
Mechanism behind gamma band activity in the pedunculopontine nucleus
(Wiley, 2011-07)
The pedunculopontine nucleus (PPN), part of the reticular activating system, modulates waking and paradoxical sleep. During waking and paradoxical sleep, EEG responses are characterized by low-amplitude, high-frequency ...
Calcium channel subtypes differentially regulate fusion pore stability and expansion
(2007)
Various studies have focused in the relative contribution of different voltage-activated Ca2+ channels (VACC) to total transmitter release. However, how Ca2+ entry through a given VACC subtype defines the pattern of ...
Class II histone deacetylases require P/Q-type Ca2+ channels and CaMKII to maintain gamma oscillations in the pedunculopontine nucleus
(Nature Publishing Group, 2018-12)
Epigenetic mechanisms (i.e., histone post-translational modification and DNA methylation) play a role in regulation of gene expression. The pedunculopontine nucleus (PPN), part of the reticular activating system, manifests ...
Pedunculopontine nucleus gamma band activity-preconscious awareness, waking, and REM sleep
(Frontiers, 2014-10)
The pedunculopontine nucleus (PPN) is a major component of the reticular activating system (RAS) that regulates waking and REM sleep, states of high-frequency EEG activity. Recently,we described the presence of high ...
Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels
(Wiley Blackwell Publishing, Inc, 2011-11)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a gradual loss of motoneurons. The majority of ALS cases are associated with a sporadic form whose etiology is unknown. Several ...