Now showing items 1-10 of 295
Effects of neutrophil depletion in the local pathological alterations and muscle regeneration. in mice injected with Bothrops jararaca snake venom
(Blackwell Publishing LtdOxfordInglaterra, 2005)
Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom
(Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, 2010)
The prominent myotoxic effects induced by Bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, BthTX-I and BthTX-II. Both myotoxins have a phospholipase A2 structure: BthTX-II is an active ...
Local tissue damage induced by Bothrops snake venoms - A review
This review focuses on the local effects induced by Bothrops venoms. These envenomation are characterized by myonecrosis, hemorrhage and edema which develop rapidly after venom inoculation. Myonecrosis is caused (a) directly, ...
Role of nitric oxide in the local and systemic pathophysiological effects induced by Bothrops asper snake venom in mice
Objective To assess the role of nitric oxide in the most relevant local and systemic manifestations in mice injected with the venom of the snake Bothrops asper. Mice were pretreated with nitric oxide synthase inhibitors, ...
Inflammation and apoptosis induced by mastoparan Polybia-MPII on skeletal muscle
(Pergamon-Elsevier B.V. Ltd, 2010-06-15)
Mastoparan firstly described as an inducer of mast cell granules exocytosis has been also related to many essential mechanisms of cell function. In skeletal muscle tissue the best characterization of mastoparan effect was ...
Myonecrosis induced by guanidine in the mouse isolated phrenic nerve diaphragm preparation
(Pergamon-elsevier Science LtdOxfordInglaterra, 1997)
Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species
The local effects induced by intramuscular inoculations of venons from six species of coral snakes were studied in mice. Venoms of Micrurus nlgrocinctus nigrocinctus, M. n . moquitensis, M. alleni, M. frontalis, M. aarinkauda ...
Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice
The mode by which coral snake (Micrurus nigrocinctus) venom affects skeletal muscle was studied using a combined approach. The venom induced early functional and structural alterations in the plasma membrane of muscle ...
Understanding and confronting snakebite envenoming: The harvest of cooperation
During 45 years, the Instituto Clodomiro Picado (ICP, University of Costa Rica) has developed an ambitious scientific, technological, productive, and social program aimed at providing a better understanding of snakes and ...
Snake venom Lys49 myotoxins: from phospholipases A2 to non-enzymatic membrane disruptors
Snake venoms often contain toxins that cause a rapid necrosis of skeletal muscle fibers, referred to as myotoxins. The most common among them are phospholipases A2 (PLA2s), enzymes that have two independent evolutionary ...