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Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity
(Suiza, 2019-10-04)
The preservation of muscle mass and muscle function after weight loss therapy is currently a considerable challenge in the fight against obesity. Muscle mass secretes proteins called myokines that have relevant functions ...
Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca2+ signals and an IL-6 autocrine loop
(American Physiological Society, 2014)
Interleukin-6 (IL-6) is an important myokine that is highly expressed in skeletal muscle cells upon exercise. We assessed IL-6 expression in response to electrical stimulation (ES) or extracellular ATP as a known mediator ...
Inflammation, physical activity, and chronic disease: An evolutionary perspective
(2020-03-01)
Low-grade inflammation is emerging as a common feature of contemporary metabolic, psychiatric, and neurodegenerative diseases. Both physical inactivity and abdominal adiposity are associated with persistent systemic low-grade ...
Effects of padel competition on brain health-related myokines
(2021-06-01)
Padel is becoming one of the most widespread racket sports that may have potential health benefits. Considering that several myokines mediate the cross-talk between skeletal muscles and the brain, exerting positive effects ...
Fibroblast growth factor-21 potentiates glucose transport in skeletal muscle fibers
(Bioscientifica, 2020)
Fibroblast growth factor 21 (FGF21) is a pleiotropic peptide hormone that is considered a myokine playing a role in a variety of endocrine functions, including regulation of glucose transport and lipid metabolism. Although ...
Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca2 signals and an IL-6 autocrine loop
(American Physiological Society, 2014)
S. Electrical stimulation induces IL-6 in skeletal muscle through
extracellular ATP by activating Ca2 signals and an IL-6 autocrine
loop. Am J Physiol Endocrinol Metab 306: E869 –E882, 2014. First
published February ...
Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells
(Elsevier B.V., 2017)
© 2016 Elsevier B.V. Duchenne muscular dystrophy (DMD) is a neuromuscular disease originated by mutations in the dystrophin gene. A promising therapeutic approach deals with functional substitution of dystrophin by utrophin, ...