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Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione
(Portland Press, 2010-01-01)
During inflammatory events, neutrophils and platelets interact to release a variety of mediators. Neutrophils generate superoxide and hydrogen peroxide, and also discharge the haem enzyme myeloperoxidase. Among numerous ...
Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione
(Portland Press, 2010-01-01)
During inflammatory events, neutrophils and platelets interact to release a variety of mediators. Neutrophils generate superoxide and hydrogen peroxide, and also discharge the haem enzyme myeloperoxidase. Among numerous ...
Serum myeloperoxidase level is Increased in heavy smokers
(2013)
Raised myeloperoxidase (MPO) serum levels are associated with endothelial dysfunction and cigarette smoking is a risk factor for cardiovascular diseases. Since myocardial infarction is associated with leukocytosis and ...
Oxidation and nitration of ribonuclease and lysozyme by peroxynitrite and myeloperoxidase
(ELSEVIER SCIENCE INC, 2009)
In spite of the many studies on protein modifications by reactive species, knowledge about the products resulting from the oxidation of protein-aromatic residues, including protein-derived radicals and their stable products, ...
Myeloperoxidase is not a good biomarker for preeclampsia prediction
(2017-12-01)
Myeloperoxidase is a proinflammatory enzyme found to be increased in patients with established preeclampsia but never investigated before the disease onset. Here we examined myeloperoxidase concentration and activity in ...
Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens
(2008-05-19)
Two new flavone glucosides, nitensosides A and B (1, 2), together with four known compounds, sorbifolin (3), sorbifolin 6-O-β-glucopyranoside (4), pedalitin (5), and pedalitin 6-O-β-glucopyranoside (6) were isolated from ...
Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens
(2008-05-19)
Two new flavone glucosides, nitensosides A and B (1, 2), together with four known compounds, sorbifolin (3), sorbifolin 6-O-β-glucopyranoside (4), pedalitin (5), and pedalitin 6-O-β-glucopyranoside (6) were isolated from ...
Electrochemical-spectroscopic-chemometric investigation of binding and inhibition of myeloperoxidase by bivalirudin: application to determination of myeloperoxidase as a biomarker for acute coronary syndrome
(Elsevier Science, 2021-07)
In this paper, we are going to report results of one of our projects in which we have investigated binding and inhibition of myeloperoxidase (MO) by bivalirudin (BV) with the help of electrochemical and spectroscopic ...
Flavonols from Pterogyne nitens and their evaluation as myeloperoxidase inhibitors
(Pergamon-Elsevier B.V. Ltd, 2008-05-01)
A myeloperoxidase inhibitory kaempferol derivative, namely pterogynoside (1), was isolated from fruits of Pterogyne nitens, along with six known flavonols, kaempferol, afzelin, kaempferitrin, quercetin, isoquercetrin and ...