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Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
(Medicina Oral S.L., 2018)
Caracterización molecular de las mutaciones presentes en los genes responsables del síndrome de Lynch
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2022)
Estresse oxidativo e lesões no DNA: papel da 8-oxoguanina na viabilidade do Trypanosoma cruzi
(Universidade Federal de Minas GeraisUFMG, 2013-03-21)
The formation of DNA lesions is one of the consequences of oxidative stress, which might result in genomic instability and lead to cell death. Guanine is the base that is most susceptible to oxidation due to its low redox ...
Metabolismo de DNA em Trypanosoma cruzi: vias de reparo mitocondrial e formação de híbridos
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2019-09-27)
Trypanosoma cruzi is a member of the Kinetoplastida and as so, present a single and unique mitochondria, called kinetoplast, which possesses several distinct features in comparison with other eukaryotes mitochondria. ...
Mutación fundadora en síndrome de Lynch tipo IIFounder mutation in Lynch syndrome
(Fundación Revista Medicina, 2016-03)
El síndrome de Lynch es la más frecuente de las neoplasias colorrectales hereditarias. Se origina por mutaciones germinales deletéreas familia-específicas en los genes que codifican proteínas de reparación del ADN: MLH1 ...
Duplo papel da proteína MSH2 no reparo de erros de pareamento no DNA e na resposta ao estresse oxidativo em tripanosomatídeos
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2015-03-09)
Different mechanisms are involved in maintaining genomic stability; among them
is the DNA Mismatch Repair (MMR). Mainly responsible for the recognition of
mismatches and insertion/deletion loops after DNA replication, ...
Genes determinantes de patogenicidade e virulência e análise parcial do genoma mitocondrial de Colletotrichum lindemuthianum, agente causal da antracnose do feijoeiro comumPathogenicity and virulence determinant genes and partial analysis of the mitochondrial genome of Colletotrichum lindemuthianum, causal agent of anthracnose of common bean
(Universidade Federal de ViçosaBRAssociações micorrízicas; Bactérias láticas e probióticos; Biologia molecular de fungos de interesseDoutorado em Microbiologia AgrícolaUFV, 2015)
Reparo de DNA em dois patógenos humanos: caracterização do gene IMP4 de Schistosoma mansini e estudos acerca do MMR, Sistema GO e taxa de mutação em Trypanosoma cruzi
(Universidade Federal de Minas GeraisUFMG, 2009-07-30)
Cells have evolved a complex set of mechanisms to appropriately respond to genotoxic damage, ensuring genomic stability. Such responses retain mutation rates in an acceptable level, through a fine-tuning balance between ...
O sistema GO em Trypanosoma cruzi: caracterização dos genes TcOGG1 e TcMYH
(Universidade Federal de Minas GeraisUFMG, 2013-12-16)
Trypanosoma cruzi is a protozoan parasite, causative of Chagas disease. Like most living organisms, it is susceptible to oxidative stress, and needs to adapt to distinct environments. Hence, DNA repair is essential for its ...
Dissociation of the X chromosome from the synaptonemal complex in the XY body of the rodent Galea musteloides
(Springer, 2013-09)
The XY body from spermatocy tes of the rodent Galea musteloides shows progressiv e changes of the sy naptonemal complex (SC) axes and the X-chromatin during pachy nema. There is a gross thickening of the X-axis and the ...