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NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration
(2023-12)
Background: Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, ...
Reduced RECK levels accelerate skeletal muscle differentiation, improve muscle regeneration, and decrease fibrosis
(2021-05)
The muscle regeneration process requires a properly assembled extracellular matrix (ECM). Its homeostasis depends on the activity of different matrix-metalloproteinases (MMPs). The reversion-inducing-cysteine-rich protein ...
Efficient muscle regeneration after highly haemorrhagic bothrops alternatus venom injection
(Elsevier, 2016)
Bothrops alternatus snake venom is particularly characterized for inducing a prominent haemorrhage and
affecting hemostasis as a consequence of 43.1% of metallo-proteinases and less than 10% of PLA2 (almost
all non-myotoxic ...
CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy
(2011)
Muscular dystrophies are diseases characterized by muscle weakness together with cycles of degeneration and regeneration of muscle fibres, resulting in a progressive decrease of muscle mass, diminished muscle force generation ...
CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy
(2011)
Muscular dystrophies are diseases characterized by muscle weakness together with cycles of degeneration and regeneration of muscle fibres, resulting in a progressive decrease of muscle mass, diminished muscle force generation ...
Inhibition of extracellular matrix assembly induces the expression of osteogenic markers in skeletal muscle cells by a BMP-2 independent mechanism
(2009)
Abstract
Background
The conversion of one cell type into another has been suggested to be, at the molecular level, the consequence of change(s) in the expression level of key ...