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Thousands of protein linear motif classes may still be undiscovered
(Public Library of Science, 2021-05-03)
Linear motifs are short protein subsequences that mediate protein interactions. Hundreds of motif classes including thousands of motif instances are known. Our theory estimates how many motif classes remain undiscovered. ...
Computational prediction of short linear motifs from protein sequences
(Springer, 2015-01)
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. SLiMs usually occur in structurally disordered ...
Mysticism in handicrafts. Case study: Seljuk Era Pottery
(Universidad del Zulia, 2019)
Relevance of CARC and CRAC Cholesterol-Recognition Motifs in the Nicotinic Acetylcholine Receptor and Other Membrane-Bound Receptors
(Elsevier Academic Press Inc, 2017-07)
Cholesterol is a ubiquitous neutral lipid, which finely tunes the activity of a wide range of membrane proteins, including neurotransmitter and hormone receptors and ion channels. Given the scarcity of available X-ray ...
Interplay between sequence, structure and linear motifs in the adenovirus E1A hub protein
(Academic Press Inc Elsevier Science, 2018-12)
E1A is the main transforming protein in mastadenoviruses. This work uses bioinformatics to extrapolate experimental knowledge from Human adenovirus serotype 5 and 12 E1A proteins to all known serotypes. A conserved domain ...
The articles.ELM resource: Simplifying access to protein linear motif literature by annotation, text-mining and classification
(Oxford University Press, 2020-01)
Modern biology produces data at a staggering rate. Yet, much of these biological data is still isolated in the text, figures, tables and supplementary materials of articles. As a result, biological information created at ...
MOTIF WRITING ON THE LMA/BF SYSTEMA ESCRITA MOTIF NO SISTEMA LMA/BF
(Universidade Federal do Rio Grande do Sul, 2020)
ELM—the eukaryotic linear motif resource in 2020
(Oxford University Press, 2019-11)
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource ...
QSLiM Finder: Improved short linear motif prediction using specific query protein data
(Oxford University Press, 2015-03)
Motivation: The sensitivity of de novo short linear motif (SLiM) prediction is limited by the number of patterns (the motif space) being assessed for enrichment. QSLiMFinder uses specific query protein information to ...
Computational Tools for the Identification and Interpretation of Sequence Motifs in Immunopeptidomes
(Wiley VCH Verlag, 2018-06)
Recent advances in proteomics and mass‐spectrometry have widely expanded the detectable peptide repertoire presented by major histocompatibility complex (MHC) molecules on the cell surface, collectively known as the ...