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Evidence of absence of Trypanosoma cruzi kinetoplast DNA methylation by restriction endonuclease analysis
(1991)
Evidence of absence of Trypanosoma cruzi kinetoplast DNA methylation by restriction endonuclease analysis. International Journal for Parasitology bd21: 863-866. Eight kinetoplast DNA samples from very different T. cruzi ...
In vitro methylation of the elongation factor EF-Tu from Escherichia coli
(1985)
The in vitro methylation of the elongation factor EF-Tu from Escherichia coli was investigated. The methylation of newly synthesized EF-Tu was obtained using lambda rifd 18 DNA as template and S-adenosyl [methyl-3H]methionine ...
DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance
(Springer, 2010-02)
Aberrant DNA methylation is considered an important epigenetic mechanism for gene inactivation. Monoclonal gammopathy of undetermined significance (MGUS) is believed to be a precursor of multiple myeloma (MM). We have ...
Screening methylation of DNA repair genes in the oral mucosa of chronic smokers
(2018-08-01)
Objective: The aim of this study was to evaluate the epigenetic changes in the process of oral carcinogenesis by screening the methylation of repair genes in chronic smokers. Design: Two groups were formed: Group 1: 16 ...
Search for methylation-sensitive amplification polymorphisms in mutant figs
(2013-07-08)
Fig (Ficus carica) breeding programs that use conventional approaches to develop new cultivars are rare, owing to limited genetic variability and the difficulty in obtaining plants via gamete fusion. Cytosine methylation ...
Search for methylation-sensitive amplification polymorphisms in mutant figs
(2013-07-08)
Fig (Ficus carica) breeding programs that use conventional approaches to develop new cultivars are rare, owing to limited genetic variability and the difficulty in obtaining plants via gamete fusion. Cytosine methylation ...
DNA methylation analysis of the tumor suppressor gene CDKN2B in Brazilian leukemia patients
(Sociedade Brasileira de Genética, 2008)
The aim of this work was to evaluate the methylation profile of the p15 (CDKN2B) gene in Brazilian patients with leukemia and to correlate the CDKN2B gene expression with the percentage of methylated CpG dinucleotides in ...
Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma
(Faculdade de Medicina / USP, 2011)
OBJECTIVES: 1) To correlate the methylation status of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter to its gene and protein expression levels in glioblastoma and 2) to determine the most reliable method for ...
Epigenetic modulation expressed as methylation changes in DNA from primary school children of two different geographical environments II
(American Scientific Publishers, 2010-06)
In previous work, proportions of the phenotypic characteristics attributable to the HSR (Hand Skill Relative, OMIM 139900) gene were found modified in primary school children from one of two distinct geographical regions ...
H19-DMR allele-specific methylation analysis reveals epigenetic heterogeneity of CTCF binding site 6 but not of site 5 in head-and-neck carcinomas: A pilot case-control analysis
(2006-02-01)
Aberrant methylation of seven potential binding sites of the CTCF factor in the differentially methylated region upstream of the H19 gene (H19-DMR) has been suggested as critical for the regulation of IGF2 and H19 imprinted ...