Now showing items 1-10 of 155
Energetics, dynamics and structure of spiking neural networks under metabolic constraints
(Universidad de Chile, 2023)
Every biological tissue or physical system is subject to physical restrictions that limit its functioning. Specifically in neural networks, energy constraints determine physically feasible states in which they can evolve. ...
Reconstruction of molecular networks involved in citokine-induced myotubes atrophy integrating microRNA and mRNA expression
(Universidade Estadual Paulista (Unesp), 2013-09-26)
The skeletal muscle atrophy is a common phenomenon in many chronic systemic diseases such a sepsis, chronic heart failure, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, AIDS and cancer. These ...
Identificação de redes gênicas de coexpressão e dos mecanismos regulatórios associados à composição mineral e qualidade de carne em bovinos
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2019-10-11)
Meat quality and mineral composition are complex traits genetically regulated. Growing evidence suggests that minerals play a central role in regulatory and physiological functions related to meat tenderness and fat ...
Systems biology and chemoinformatics methods for biomining and systems metabolic engineering applications
(Universidad de Chile, 2014)
In the first chapter, this thesis aims to demonstrate the great potential of Constraint-Based Reconstruction and Analysis (COBRA) methods for studying and predicting specific phenotypes in the bacterium Acidithiobacillus ...
Estudo químico dos fungos Stachybotrys levispora e Curvularia inaequalis: uso da rede molecular para a identificação de novos metabólitos
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2019-05-03)
Saprobic fungus are being used as an alternative strategy to reduce the use of pesticides harmful to the environment. These microorganisms produce substances capable of inhibiting pathogens that affect agriculture. The ...
Estruturas de controle de biorreator baseadas em fluxos metabólicos para fermentações micro-aeradas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Engenharia Química - PPGEQCâmpus São Carlos, 2021-04-15)
The supply of oxygen as a limiting nutrient in bioreactors is a challenge, as microorganisms may have different metabolic requirements, besides the difficulty of measuring this variable in low levels. Despite the obstacles, ...
Contributions to metabolic network : Reconstructions
(2021-08-10)
Esta tesis presenta contribuciones para la reconstrucción a escala del genoma de las redes metabólicas y sus restricciones basadas en análisis. Se presenta una breve descripción general del modelado y la reconstrucción de ...