Though introduced recently, complex networks research has grown steadily because of its potential to represent, characterize and model a wide range of intricate natural systems and phenomena. Because of the intrinsic ...

Many complex systems can be described as networks exhibiting inner organization as communities of nodes. The identification of communities is a key factor to understand community-based functionality. We propose a family ...

Back ground. The emergence of functions in biological systems is a long-standing issue that can now be addressed at the cell level with the emergence of high throughput technologies for genome sequencing and phenotyping. ...

In this work we propose an eigenvalue optimization approach to ensure steady state stability of the Embden-Meyerhof-Parnas pathway, the pentose-phosphate pathway and the phosphotransferase system of Escherichia coli. The ...

The homeostasis of plants under environmental constraints may be maintained by alterations in the organization of their physiological networks. The ability to control a network depends on the strength of the connections ...

Background: What an organism needs at least from its environment to produce a set of metabolites, e.g. target(s) of interest and/or biomass, has been called a minimal precursor set. Early approaches to enumerate all minimal ...

This work proposes a procedure for simultaneous parameters identifiability and estimation in metabolic networks in order to overcome difficulties associated with lack of experimental data and large number of parameters, ...