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The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition markers, E-cadherin and β-catenin, in prostate cancer
(2010)
The epithelial-mesenchymal transition (EMT) is considered a key step in tumor progression, where the invasive cancer cells change from epithelial to mesenchymal phenotype. During this process, a decrease or loss in adhesion ...
The inflammatory profile of the tumor microenvironment, orchestrated by cyclooxygenase-2, promotes epithelial- mesenchymal transition
(Frontiers Media, 2021)
The tumor microenvironment (TME) corresponds to a complex and dynamic
interconnection between the extracellular matrix and malignant cells and their
surrounding stroma composed of immune and mesenchymal cells. The TME ...
Evidence of epithelial-mesenchymal transition in canine prostate cancer metastasis
(Elsevier B.V., 2015-06-01)
The epithelial mesenchymal transition (EMT) is a fundamental event responsible for the invasiveness and metastasis of epithelial tumours. The EMT has been described in many human cancers, but there are few reports of this ...
Demonstration of epithelial-mesenchymal transition in kidney - The contribution of a coupled histochemical and immunohistochemical staining with Periodic Acid-Thionin Schiff
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Traditional Periodic Acid Schiff has been extensively used, coupled with immunohistochemistry for epithelia or mesenchymal cells, to highlight renal tubular basement membrane (TBM). We recently tried to perform such technique ...
The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines
(Wolters kluwer medknow publications, 2018-06)
It has been reported that one of the factors that promotes tumoral progression is the abnormal activation of the epithelial-mesenchymal transition program. This process is associated with tumoral cells acquiring invasive ...
Competing endogenous RNA networks in the epithelial to mesenchymal transition in diffuse-type of gastric cancer
(MDPI, 2020)
The diffuse-type of gastric cancer is associated with epithelial to mesenchymal transition. Loss of E-cadherin expression is the hallmark of this process and is largely due to the upregulation of the transcription factors ...
Evidence of epithelial-mesenchymal transition in canine prostate cancer metastasis
(Elsevier B.V., 2015)
Fibroblasts induce epithelial to mesenchymal transition in breast tumor cells which is prevented by fibroblasts treatment with histamine in high concentration
(Elsevier, 2014-06)
Epithelial to mesenchymal transition (EMT) of cancer cells is an essential process in cancer progression. Cancer cells that undergone EMT loose cell–cell contacts, acquire mesenchymal properties and develop migratory and ...
Usual interstitial pneumonia and smoking-related interstitial fibrosis display epithelial to mesenchymal transition in fibroblastic foci
(W B Saunders Co Ltd, 2014-09-01)
Background: Fibroblastic foci (FF) are a major histological feature of usual interstitial pneumonia (UIP) in idiopathic pulmonary fibrosis (IPF) and collagen vascular diseases (non-IPF). In addition, FF are occasionally ...
Gamma secretase inhibitor impairs epithelial-to-mesenchymal transition induced by TGF-β in ovarian tumor cell lines
(Elsevier Ireland, 2017-01)
Ovarian cancer is characterized by being highly metastatic, a feature that represents the main cause of failure of the treatment. This study investigated the effects of γ-secretase inhibition on the TGF-β-induced ...