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Protein-lipid interactions modulate lipid composition, membrane dynamics and structure
(Nova Science Publishers, 2018)
The interactions of proteins with membrane surfaces are important to many biological processes, including signaling, recognition, and membrane trafficking, cell division and cell structure. When the Fluid Mosaic Model (FMM) ...
Lipid Droplets: Structure, Composition, Formation and Function. Connection with the Endoplasmic Reticulum
(Nova Science Publishers, 2019)
Fatty acids (FAs) are important compounds either used for energy production through β-oxidation, for membrane lipid synthesis, or for production of lipid mediators (oxylipins) through oxidations. FAs are also cytotoxic and ...
Nitric oxide and membrane lipid peroxidation in photosynthetic and non-photosynthetic organisms under several stress conditions
(Frontiers Media, 2017)
Oxidative damage to lipids was characterized in terms of the nature of the oxidant, the type of lipid, and the severity of the oxidation (Simontacchi et al., 2011). Even though malondialdehyde detection with the thiobarbituric ...
Important advances in the knowledge of lipid droplets in the last six decades
(Nova Science Publishers, 2019)
Lipid droplets are highly dynamic cytoplasmic (and nuclear) cell organelles composed of a core of neutral lipids (triglycerides (TG) and cholesterol ester (CE)) surrounded by a monolayer of phospholipids with embedded ...
The Role of Water in the Responsive Properties in Lipid Interphase of Biomimetic Systems
(IntechOpen, 2019)
The lack of details in the hydration properties of lipid bilayers hinders the design of biomimetic systems that, as liposomes and vesicles, may be used for biotechnological and medical purposes. In this chapter, studies ...
Protein Transport into and Across Haloarchaeal Cytoplasmic Membranes
(Springer, 2011)
Several pathways have evolved in the three domains of life to facilitate membrane protein insertion and the transport of proteins across lipid membranes. Haloarchaea employ the universally conserved Sec pathway, which ...
Bacterial S-Layer Proteins for Stabilization of Food Ingredients Encapsulated in Liposomes
(Humana Press, 2021)
To protect food ingredients from degradation that can occur in the harsh environmental conditions of the gastrointestinal tract, many different oral delivery systems such as liposomes have been developed. However, liposomes ...
Flunitrazepam–Membrane Binding: A Sensor for Drug-Induced GABAA-R and Membrane Structure Changes
(Elsevier Academic Press Inc., 2016)
Flunitrazepam (FNZ) is a sedative–hypnotic benzodiazepine with important therapeutic usefulness and significant abuse liability. Its capability to induce anterograde amnesia favors FNZ use as a “date-rape drug” administered ...
Chapter 3 - Strategies to reduce lipid consumption
(Elsevier, 2020)
Lipids are macronutrients that have important functions in the body like storing energy, signaling, and acting as structural components in cell membranes. However, the daily consumption of a high-lipid diet has been involved ...
Laurdan Studies of Membrane Lipid-Acetylcholine Receptor Protein Interactions
(Humana Press, 2007)
The extrinsic fluorescent probe Laurdan (6-dodecanoyl-2-dimethylamino naphthalene) exhibits extreme sensitivity to the polarity and to the molecular dynamics of the dipoles in its environment. Dipolar relaxation processes ...