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Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?
(Frontiers Media, 2020-08)
G-protein–coupled receptors (GPCRs) are targets for around one third of currently approved and clinical prescribed drugs and represent the largest and most structurally diverse family of transmembrane signaling proteins, ...
Hormone receptors in breast cancer: more than estrogen receptorsReceptores hormonales en cáncer de mama: receptores de estrógenos y algo más
(Medicina Buenos Aires, 2019-12)
Seventy per cent of breast cancers are luminal carcinomas that express alpha estrogen receptors (ER). For several decades, its expression has been used as a therapeutic target in patients with breast cancer. These therapies ...
Avaliação dos efeitos vasculares da Angiotensina-(1-9)
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2020-01-22)
Identificação e expressão do receptor MAS no coração em diferentes condições fisiológicas e patológicas.
(Universidade Federal de Minas GeraisUFMG, 2007-04-02)
Cardiac remodelling occurs through cellular alterations in different physiological and pathological conditions which are still poorly understood. The reninangiotensin system is known to have an important role in this ...
Inotropicos y vasopresores
(Universidad de La SabanaDepartamento de Farmacología Clínica y Terapéutica, 2014)
Algunos también son inotrópicos y se utilizan para mejorar el gasto cardiaco, particularmente en pacientes con insuficiencia impelente del ventrículo izquierdo o choque cardiógeno. El cuadro 20-11-3 incluye un resumen de ...
Avaliação de sistemas vasoativos: papel dos autoanticorpos na preeclâmpsia
(Universidade Federal de Minas GeraisUFMG, 2010-10-08)
Preeclampsia (PE) is a leading cause of maternal death and a major contributor to maternal and perinatal morbitidy. However, the mechanisms implicated in this disease are still poorly understood. Recent studies have shown ...
Contribución al problema de modelación de receptores insertos en membrana : Desarrollo de modelos de receptores de serotonina usando nuevos métodos en modelación molecular
(Universisdad de Chile, 2002)
En esta tesis, los receptores serotoninergicos 5-HT2A y 5HT2c fueron escogidos como modelos de familia mas amplia de receptores insertos en membranas y acoplados a proteínas G con el propósito de estudiar las interacciones ...
AT2 and MAS (but not AT1) angiotensinergic receptors in the medial amygdaloid nucleus modulate the baroreflex activity in rats
(2019-09-01)
The medial amygdaloid nucleus (MeA) is a limbic structure that has been demonstrated to be part of the central circuitry regulating baroreflex function. However, the local neurochemical mechanisms involved in baroreflex ...