Now showing items 1-10 of 42
Mannose binding lectin gene (MBL2) functional polymorphisms are associated with systemic lupus erythematosus in southern Brazilians
(ELSEVIER SCIENCE INC, 2011)
Susceptibility to systemic lupus erythematosus (SLE) has been associated with immunologic, environmental, and genetic factors. To uncover a possible association between MBL2 gene polymorphisms and SLE, we analyzed functional ...
Post-infectious bronchiolitis obliterans and mannose-binding lectin insufficiency in Argentinean children
(Wiley Blackwell Publishing, Inc, 2015-08)
Background and objective: Post‐infectious bronchiolitis obliterans (PIBO) is a severe disorder following acute lower pulmonary infection in young children, especially caused by adenovirus. Mannose‐binding lectin (MBL) ...
Mannose-binding lectin gene as a modifier of the cystic fibrosis phenotype in Argentinean pediatric patients
(Elsevier Science, 2014-08)
Background There is a considerable variation in the phenotype and course of the disease in cystic fibrosis (CF) even in patients with the same CFTR genotype, suggesting that other factors are important for prognosis. ...
Short Report: Mannose-Binding Lectin and Toll-Like Receptor Polymorphisms and Chagas Disease in Chile
(American Society of Tropical Medicine and Hygiene, 2012)
Mannose-binding lectin (MBL) and Toll-like receptor (TLR) polymorphisms may influence susceptibility and manifestation of Trypanosoma cruzi infection. In northern Chile, we examined 61 asymptomatic patients with chronic ...
Association of MBL2, TGF-beta 1 and CD14 gene polymorphisms with lung disease severity in cystic fibrosis
(Soc Brasileira Pneumologia TisiologiaBrasilia DfBrasil, 2009)
Association between mannose-binding lectin and interleukin-1 receptor antagonist gene polymorphisms and recurrent vulvovaginal candidiasis
(SPRINGER HEIDELBERGHEIDELBERG, 2012)
Objective The influence of functional polymorphisms in the genes coding for mannose-binding lectin (MBL) and interleukin-1 receptor antagonist (IL-1ra) on recurrent vulvovaginal candidiasis (RVVC) were examined in an urban ...
Mannose-binding lectin gene polymorphism and risk factors for cardiovascular disease in postmenopausal women
(Elsevier B.V., 2014-09-01)
Background: Inflammatory responses may be altered in postmenopausal women and predispose to cardiovascular disease (CVD). Genetic factors can also influence susceptibility to CVD. Mannose-binding lectin (MBL) is a component ...
Mannose-binding lectin complement pathway plays a key role in complement activation by Paracoccidioides brasiliensis
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Paracoccidioides brasiliensis (Pb) is a dimorphic fungal pathogen that causes paracoccidioidomycosis the most severe deep mycosis from South America Although cell mediated immunity is considered the most efficient protective ...
Phylogenetic nomenclature and evolution of mannose-binding lectin (MBL2) haplotypes
(BIOMED CENTRAL LTD, 2010)
Background: Polymorphisms of the mannose-binding lectin gene (MBL2) affect the concentration and functional efficiency of the protein. We recently used haplotype-specific sequencing to identify 23 MBL2 haplotypes, associated ...