Buscar
Mostrando ítems 1-10 de 88
MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E-2-mediated M2 generation
(Public Library Science, 2015-02-23)
Macrophages dictate both initiation and resolution of inflammation. During acute inflammation classically activated macrophages (M1) predominate, and during the resolution phase alternative macrophages (M2) are dominant. ...
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2 prostaglandin E2 pathway
(Wiley, 2017)
Bone fractures are among the most common orthopaedic problems that affect individuals of all ages. Immediately after injury, activated macrophages dynamically contribute to and regulate an acute inflammatory response that ...
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
(John Wiley and Sons Inc., 2017)
Bone fractures are among the most common orthopaedic problems that affect individuals of all ages. Immediately after
injury, activated macrophages dynamically contribute to and regulate an acute inflammatory response that ...
Immunohistochemical evaluation of macrophage activity and its relationship with apoptotic cell death in the polar forms of leprosy
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2010)
The objective of the present study was to investigate the correlation between macrophage activity and apoptosis in the polar forms of leprosy because the immunopathological phenomena involved in these forms are still poorly ...
Macrophage Polarization and Alveolar Bone Healing Outcome: Despite a Significant M2 Polarizing Effect, VIP and PACAP Treatments Present a Minor Impact in Alveolar Bone Healing in Homeostatic Conditions
(2021-12-21)
Host inflammatory immune response comprises an essential element of the bone healing process, where M2 polarization allegedly contributes to a favorable healing outcome. In this context, immunoregulatory molecules that ...
Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3
(Nature Publishing Group, 2017-02)
In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in ...