Now showing items 1-10 of 131
Latenciação e formas avançadas de transporte de fármacos
(Divisão de Biblioteca e Documentação do Conjunto das Químicas da Universidade de São Paulo, 2005-06-01)
O processo de modificação molecular denominado latenciação é revisto, apresentando formas avançadas no transporte de fármacos, utilizando macromoléculas como transportadores e sistemas de liberação sítio-específica como: ...
GTP-mediated macromolecular interactions: The common features of different systems
G proteins that serve to transduce external signals in membranes share with protein synthesis factors and tubulin structural and functional features that are common to proteins that participate in reversible GTP-mediated ...
Nontemplate-driven polymers: clues to a minimal form of organization closure at the early stages of living systems
The emergence of the first polymers played an essential role in the transition from the physicochemical to the biological domain, a perception that embodied many different world paradigms relying on only one primal polymer. ...
ROLE OF THE LINKING OF METALLIC CENTERS TO MACROMOLECULAR AND OLIGOMERIC SYSTEMS IN THE PYROLYTIC PRODUCTS
(Sociedad Chilena de Química, 2008)
Specific macromolecular interactions between tau and the microtubule system
(Kluwer Academic Publishers, 1992)
The microtubule-associated protein Tau, a major component of brain microtubules, shares common repeated C-terminal sequences with the high molecular-weight protein MAP-2. It has been shown that tau peptides V187-G204 and ...
Microparticles as a Strategy for Low-Molecular-Weight Heparin Delivery
The aims of this work were preparation and physical-chemical characterization of a microparticulate release system for delivery of enoxaparin sodium (ENX), a low-molecular-weight heparin, as a potential vehicle for ...
Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes
Snake venom serine proteinases (SVSPs) are hemostatically active toxins that perturb the maintenance and regulation of both the blood coagulation cascade and fibrinolytic feedback system at specific points, and hence, are ...