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Biosimilar monoclonal antibodies in Latin America
(IntechOpen, 2021)
Antibodies, also known as immunoglobulins, are complex glycoproteins produced by B-cells against foreign substances as part of the adaptive immune response [1, 2]. The invention of the hybridoma technology in 1975 by Köhler ...
Genetic engineering of antibody molecules
(Wiley VCH Verlag, 2015)
Antibodies are proteins produced by the immune system to combat pathogens and have long been appreciated for their exquisite specificity. The development of the hybridoma technology made it possible to immortalize single ...
Insulysin
(Elsevier, 2013)
Insulysin appears to be responsible for the majority of the insulin-degrading activity in most cell lysates. It is inhibited by both chelating agents and alkylating agents. Because of its high affinity for insulin, it is ...
Desing, Synthesis and applications of short-peptide and peptidomimetic ligands for affinity chromatography
(Nova Science Publishers, 2018)
In the last few years many novel and alternative protein purificationprotocols have been designed using immobilized short-peptides orpeptidomimetics as ligands for affinity chromatography. These ligandsare easy to synthesize ...