Now showing items 1-10 of 203
Monoclonal Antibody for Patients with Covid-19
(Massachusetts Medical Society, 2021-03-25)
The ACTIV-3/TICO LY-CoV555 Study Group (Dec. 22)1 hypothesized that low penetration of the antibody into the infected lungs might explain the lack of benefit of bamlanivimab (LY-CoV555) in hospitalized patients with ...
Biosimilar monoclonal antibodies in Latin America
Antibodies, also known as immunoglobulins, are complex glycoproteins produced by B-cells against foreign substances as part of the adaptive immune response [1, 2]. The invention of the hybridoma technology in 1975 by Köhler ...
Antitumor properties of an anti-idiotypic monoclonal antibody in relation to N-glycolyl-containing gangliosides
(Spandidos Publications, 2000-07)
We examined the antitumor effects of 1E10 monoclonal antibody, an anti-idiotypic IgG to an IgM monoclonal antibody, named P3, that reacts specifically with N-glycolyl-containing gangliosides and also recognizes antigens ...
Neutralizing monoclonal antibodies to fight HIV-1 : on the threshold of success
Anti-human immunodeficiency virus type-1 (anti-HIV-1) neutralizing monoclonal antibodies are broadening the spectrum of pre- and post-exposure treatment against HIV-1. A better understanding of how these antibodies develop ...
Uso de anticuerpo monoclonal para tratamiento de osteonecrosis de talo y cabeza humeral bilaterales secundario al uso de corticoides por leucemia linfoide aguda. Reporte de casoUsing Monoclonal Antibody for Treatment of Bilateral Talar and Humeral Head Osteonecrosis Secondary at the Use of Corticosteroids for Acute Lymphoid Leukemia. A Case Report
Genetic engineering of antibody molecules
(Wiley VCH Verlag, 2015)
Antibodies are proteins produced by the immune system to combat pathogens and have long been appreciated for their exquisite specificity. The development of the hybridoma technology made it possible to immortalize single ...
Immunomodulatory monoclonal antibodies in combined immunotherapy trials for cutaneous melanoma
(Frontiers Media S.A., 2017-08)
In the last few years, there has been a twist in cancer treatment toward immunotherapy thanks to the impressive results seen in advanced patients from several tumor pathologies. Cutaneous melanoma is a highly mutated and ...
Production of a monoclonal antibody against serum immunoglobulin M of South American camelids and assessment of its suitability in two immunoassays
(American Association of Veterinary Laboratory Diagnosticians, 2014-09)
A monoclonal antibody (mAb) was produced against immunoglobulin M (IgM) of South American camelids. A single radial immunodiffusion (SRID) assay and a competitive enzyme-linked immunosorbent assay (ELISA) were developed ...