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Development of an automated MODS plate reader to detect early growth of Mycobacterium tuberculosis
(Wiley, 2011)
In this work, an automated microscopic observation drug susceptibility (MODS) plate reader has been developed. The reader automatically handles MODS plates and after autofocussing digital images are acquired of the ...
Low-cost 3D-printed inverted microscope to detect Mycobacterium tuberculosis in a MODS culture
(Elsevier, 2022)
MODS, an assay for diagnosis of tuberculosis and drug-susceptibility, is based in the microscopic observation of the characteristic cords of Mycobacterium tuberculosis colonies grown in liquid media. An inverted optical ...
Direct determination of pyrazinamide (PZA) susceptibility by sputum microscopic observation drug susceptibility (MODS) culture at neutral pH: the MODS-PZA assay
(American Society for Microbiology, 2020)
Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens, due to its particular action on the persistent forms of Mycobacterium tuberculosis. However, no drug susceptibility test (DST) is ...
Second-line drug susceptibility breakpoints for Mycobacterium tuberculosis using the MODS assay
(International Union Against Tuberculosis and Lung Disease, 2014)
OBJECTIVE: To establish breakpoint concentrations for the fluoroquinolones (moxifloxacin [MFX] and ofloxacin [OFX]) and injectable second-line drugs (amikacin [AMK], kanamycin [KM] and capreomycin [CPM]) using the microscopic ...
Alternative cost-effective media to facilitate MODS culture for diagnostics of tuberculosis
(Elsevier, 2022)
Most culture-based methods for tuberculosis diagnosis remain low-cost options for low- and mid-income countries. The MODS culture is a rapid and low-cost assay to diagnose tuberculosis and determine drug susceptibility. ...
Evaluation of three alternatives cost-effective culture media for Mycobacterium tuberculosis detection and drug susceptibility determination using the microscopic observation drug susceptibility (MODS) assay
(Elsevier, 2022)
Tuberculosis phenotypic detection assays are commonly used in low-resource countries. Therefore, reliable detection methods are crucial for early diagnosis and treatment. The microscopic observation drug susceptibility ...
Validez De La Escala De Disfunción Orgánica Múltiple (Mods) Para Precedir La Mortalidad En Pacientes Con Abdomen Abierto.
(Universidad Nacional de Trujillo, 2014)
Caenorhabditis elegans serotonin-gated chloride channel MOD-1 as a novel drug target for anthelmintic therapy
(Sociedad Argentina de Biofísica, 2020)
Serotonin-gated ion channels (5-HT3) belong to the family of Cys-loop receptors, which are pentameric proteins that mediate fast synaptic transmission. In mammals, 5-HT3 are non-selective cationic channels that can be ...