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Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation
(Springer, 2015)
The first manually curated genome-scale metabolic model for Salinispora tropica strain CNB-440 was constructed. The reconstruction enables characterization of the metabolic capabilities for understanding and modeling the ...
Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage
(Public Library of Science, 2017)
It was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana ...
Expanding Metabolic Capabilities Using Novel Pathway Designs: Computational Tools and Case Studies
(Wiley-VCH Verlag, 2019)
Design and selection of efficient metabolic pathways is critical for the success of metabolic engineering endeavors. Convenient pathways should not only produce the target metabolite in high yields but also are required ...
Metabolic Syndrome Criteria As Predictors of Insulin Resistance, Inflammation and Mortality in Chronic Hemodialysis Patients
(Mary Ann Liebert, Inc, 2014-10-01)
Background: Chronic kidney disease (CKD) and metabolic syndrome are characterized by overlapping disorders, including glucose intolerance, hypertension, dyslipidemia, and, in some cases, obesity. However, there are no ...
Use of genome-scale models to get new insights into the marine actinomycete genus Salinispora
(BioMed Central Ltd., 2019)
Background: There is little published regarding metabolism of Salinispora species. In continuation with efforts performed towards this goal, this study is focused on new insights into the metabolism of the three-identified ...
Comparative transcriptomic analysis of Streptococcus thermophilus TH1436 and TH1477 showing different capability in the use of galactose
(Frontiers in Microbiology, 2019)
Metabolic modelling and flux analysis of microorganisms from the Atacama Desert used in biotechnological processes
(Springer Netherlands, 2018)
Metabolic modelling is a useful tool that enables the rational design of metabolic engineering experiments and the study of the unique capabilities of biotechnologically important microorganisms. The extreme abiotic ...
Foetoplacental epigenetic changes associated with maternal metabolic dysfunction
(2018)
Metabolic-related diseases are attributed to a sedentary lifestyle and eating habits, and there is now an increased awareness regarding pregnancy as a preponderant window in the programming of adulthood health and disease. ...