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Requirements for PKC-augmented JNK activation by MKK4/7
(Elsevier, 2008)
The c-Jun N-terminal kinases (JNKs) are activated in response to stress, DNA damage, and cytokines by MKK4 and MKK7. We recently demonstrated that PKC can augment the degree of JNK activation by phosphorylating JNK, which ...
Cloning and chromosomal localization of the gene coding for human protein kinase CK1
(1994)
A cDNA clone coding for human protein kinase CK1 (casein kinase 1) has been isolated and sequenced demonstrating that it corresponds to a homolog of the CK1α form found in bovine brain. The derived amino acid sequence of ...
Experimental evidence of MAP kinase gene expression on the response of intestinal anti-inflammatory drugs
(Elsevier B. V., 2015-09-01)
The etiopathogenesis of inflammatory bowel disease (IBD) is unclear and further understanding of the mechanisms that regulate intestinal barrier integrity and function could give insight into its pathophysiology and mode ...
Role of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration
(Frontiers in Bioscience, 2017)
The MAP Kinases are Differently Utilized by CD28 and CD2 Adhesion Pathways in Superantigen-Activated Jurkat T cells
(Sociedad de Biología de Chile, 2003)
The long arm of BRAF V600E gets to mTORC1
(Wiley, 2009-03)
Despite the disappointing results of early clinical studies, targeting the BRAF ⁄ MEK⁄ extracellular signal-regulated kinase (ERK), mitogen-activated protein kinase (MAPK) pathway is still a subject of investigation due ...