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Autoantibodies as biomarkers for interstitial lung disease in idiopathic inflammatory myositis and systemic sclerosis: The case of anti-eIF2B antibodies
(Elsevier, 2020-01)
Objectives: Serum autoantibodies are pivotal for the early detection of systemic autoimmune rheumatic diseases such as Systemic Sclerosis (SSc) and Poly/Dermatomyositis (PM/DM), and in some cases are associated with organ ...
Association with amino acids does not enhance efficacy of polymerized liposomes as a system for lung gene delivery
(Frontiers Research Foundation, 2016-04)
Development of improved drug and gene delivery systems directly into the lungs is highly desirable given the important burden of respiratory diseases. We aimed to evaluate the safety and efficacy of liposomes composed of ...
Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
(Pergamon-Elsevier Science Ltd, 2014-06)
A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably ...
Exploring Boron Neutron Capture Therapy for non-small cell lung cancer
(Istituti Editoriali e Poligrafici Internazionali, 2014-12)
Boron Neutron Capture Therapy (BNCT) is a radiotherapy that combines biological targeting and high LET radiation. It consists in the enrichment of tumour with 10B and in the successive irradiation of the target with low ...
Hazardous effects of urban air particulate matter acute exposure on lung and extrapulmonary organs in mice
(Academic Press Inc Elsevier Science, 2020-03)
Air particulate matter (PM) can lead to extrapulmonary adverse reactions in organs such as liver and heart either by particle translocation from the lung to the systemic circulation or by the release of lung mediators. ...
Molecular mechanisms and cellular contribution from lung fibrosis to lung cancer development
(MDPI, 2021-11-10)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung disease (ILD) of unknown aetiology, with a median survival of 2–4 years from the time of diagnosis. Although IPF has unknown aetiology ...
Expression of heme oxygenase-1 in non small cell lung cancer (NSCLC) and its correlation with clinical data
(Elsevier Ireland, 2012-07)
While changes in heme oxygenase (HO-1) in lung cancer have already been reported, conflicting results were obtained for enzyme expression in human lung cancer specimens. Therefore, the aim of this work was to study HO-1 ...
The discovery BPD (D-BPD) program: Study protocol of a prospective translational multicenter collaborative study to investigate determinants of chronic lung disease in very low birth weight infants
(BioMed Central, 2019-07-06)
Background: Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated with ...
Controlled Drug Delivery via the Lung
(John Wiley & Sons Inc, 2021)
The lungs fulfill the vital function of transporting and exchanging breathing air. The respiratory tract is considered an excellent delivery route for local and noninvasive administration of active ingredients, even when ...