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Lopap: A non-inflammatory and cytoprotective molecule in neutrophils and endothelial cells
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Lopap (Lonomia obliqua prothrombin activator protease) is a member of the lipocalin family isolated from the extract of L obliqua bristles. Lopap displays serine protease-like activities, including coagulation disturbance, ...
Effects of Lopap on Human Endothelial Cells and Platelets
(Karger, 2001-05)
Severe consumption coagulopathy has been detected in rats after Lopap (a prothrombin activator from Lonomia obliqua caterpillar bristles) infusion and in humans after accidental contact with L. obliqua bristles. However, ...
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-10-01)
Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to ...
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-10-01)
Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to ...
The Reversal of the Anticoagulant and Anti-hemostatic Effect of LMWH by rLopap
(Federation Amer Soc Exp Biol, 2015-04-01)
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014)
A lipocalin sequence signature modulates cell survival
(ELSEVIER SCIENCE BV, 2010)
Lipocalins are beta-barrel proteins, which share three conserved motifs in their amino acid sequence. In this study, we identified by a peptide mapping approach, a seven-amino acid sequence related to one of these motifs ...
Caracterização funcional do LOPAP (ativador de protrombina da lagarta Lanomia oblíqua)
(Universidade Federal de São Paulo (UNIFESP), 2002)
A lagarta Lonomia obliqua é encontrada no sul do Brasil, e o contato da pele humana com suas cerdas, em forma de "espinhos", causa entre outros sintomas, uma severa síndrome hemorrágica devido a coagulopatia de consumo, ...
In vivo characterization of Lopap, a prothrombin activator serine protease from the Lonomia obliqua caterpillar venom
(Elsevier B.V., 2001-06-01)
Increasing occurrence of hemorrhagic syndrome in man, caused by contact with Lonomia obliqua caterpillars, has been reported in Southern Brazil in the past 10 years. the L. obliqua venom causes a severe consumptive ...
Purification and initial characterization of a novel protein with factor Xa activity from Lonomia obliqua caterpillar spicules
(John Wiley & Sons LtdChichesterInglaterra, 2005)