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Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
(2017-10-01)
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...
Lipid peroxidation modifies the assembly of biological membranes "The lipid Whisker Model"
(Frontiers Media, 2015-01)
The aim of this opinion article is to point out the basic principles that modify the assembly of biological membranes during lipid peroxidation. With this objective in mind I describe: the structural and functional ...
Ca2+ adsorption to lipid membranes and the effect of cholesterol in their composition
(Elsevier Science, 2010-03)
The aim of this work is to determine the binding of ionic calcium (Ca2+) to lipid membranes in which the availability of the phosphate groups to the aqueous phase is modified by the degree of saturation of the lipids and ...
Editorial: Impact of lipid peroxidation on the physiology and pathophysiology of cell membranes.
(The Ohio State University, 2016-09)
The present research topic might be divided in two major blocks. The first one deals on the mechanisms of lipid peroxidation under physiological and pathophysiological conditions. The second one highlight the different ...
Lipid peroxidation modifies the picture of membranes from the “Fluid Mosaic Model” to the “Lipid Whisker Model”
(Elsevier Masson, 2012-01)
The “Fluid Mosaic Model”, described by Singer and Nicolson, explain both how a cell membrane preserves a critical barrier function while it concomitantly facilitates rapid lateral diffusion of proteins and lipids within ...
Differential expression of potassium channels in placentas from normal and pathological pregnancies: Targeting of the K ir 2.1 channel to lipid rafts
(2012)
Potassium channels play important physiological roles in human syncytiotrophoblasts (hSTBs) from placenta, an epithelium responsible for maternal-fetal exchange. Basal and apical plasma membranes differ in their lipid and ...
Molecular interactions of an ornithine-rich pH-responsive self-Assembling peptide with a model lipid membrane: Conformational aspects
(2016-09-01)
Investigating interactions of designed peptide-based biomaterials with lipid membranes is important for applications in nanobiotechnology. Here the interaction of an ornithine-rich pH-responsive peptide called P11-5 with ...