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Surface mixing of products and substrate of PLA2 in enzyme-free mixed monolayers reproduces enzyme-driven structural topography
(Elsevier Science, 2013-05)
It was proposed that topographic changes in lipid monolayers hydrolyzed by lipolytic enzymes such as Phospholipase A2 (PLA2) are a consequence of enzyme activity at the surface. Lateral packing defects that arise from lipid ...
Dipolar interactions between domains in lipid monolayers at the air-water interface
(Royal Society of Chemistry, 2016-05)
A great variety of biologically relevant monolayers present phase coexistence characterized by domains formed by lipids in an ordered phase state dispersed in a continuous, disordered phase. From the difference in surface ...
Modulation of the domain topography of biphasic monolayers of stearic acid and dimyristoyl phosphatidylcholine
(Elsevier Ireland, 2012-02)
The phase diagram of mixed monolayers composed of dimyristoyl phosphatidylcholine (DMPC) and stearic acid (SA) on different subphases was previously reported. It was observed that on acid subphases, liquid-condensed domains ...
Refractive index and thickness determination in Langmuir monolayers of myelin lipids
(Elsevier Science, 2017-05)
Langmuir monolayers at the air/water interface are widely used as biomembrane models and for amphiphilic molecules studies in general. Under controlled intermolecular organization (lateral molecular area), surface pressure, ...
Stiffness of lipid monolayers with phase coexistence
(American Chemical Society, 2013-08)
The surface dilational modulus (or compressibility modulus) has been previously studied for monolayers composed of pure materials, where a jump in this modulus was related with the onset of percolation as a result of the ...
Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
(2017-10-01)
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...
Evidence of photoinduced lipid hydroperoxidation in Langmuir monolayers containing Eosin Y
(2018-11-01)
Photodynamic therapy (PDT) efficiency depends on many factors including the incorporation of the photosensitizer (PS) in cell membranes and possible lipid hydroperoxidation. In this study, we show that hydroperoxidation ...
Interaction of dextran derivatives with lipid monolayers and the consequential modulation of the film properties
(Elsevier Ireland, 2017-04)
Polysaccharides have been associated with various biological functions through their binding to membranes, but their specific role is still under debate. The aim of this work was to study the interaction of cationic and ...
Improved prediction of bilayer and monolayer properties using a refined BMW-MARTINI force field
(Elsevier Science, 2016-08-31)
Coarse-grained (CG) models allow enlarging the size and time scales that are reachable by atomistic molecular dynamics simulations. A CG force field (FF) for lipids and amino acids that possesses a polarizable water model ...
Comparative study of liponucleosides in Langmuir monolayers as cell membrane models
(ELSEVIER SCIENCE BV, 2011)
Liponucleosides may assist the anchoring of nucleic acid nitrogen bases into biological membranes for tailored nanobiotechnological applications. To this end precise knowledge about the biophysical and chemical details at ...