Now showing items 1-10 of 295
The antifungal compound butenafine eliminates promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis
The production of ergosterol lipid, important for the Leishmania membrane homeostasis, involves different enzymes. This pathway can be blocked to azoles and allylamines drugs, such as Butenafine. The aim of the present ...
Effect of natural naphthoquinones in BALB/c mice infected with Leishmania amazonensis and L. venezuelensis
(Trop. Med. Parasitol, 1992)
Plumbagin, 3,3’-biplumbagin and 8,8'-biplumbagin are naphthoquinones isolated by activity-directed fractionation from a Bolivian plant; Pera benensis, used in folk medicine as treatment of cutaneous leishmaniasis caused ...
Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags
(Instituto Oswaldo Cruz, Ministério da Saúde, 2007-09-01)
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from ...
Photodynamic therapy for American cutaneous leishmaniasis: The efficacy of methylene blue in hamsters experimentally infected with Leishmania (Leishmania) amazonensis
(Academic Press Inc. Elsevier B.V., 2011-08-01)
The aim of this study was to investigate the effectiveness of Photodynamic Therapy (PDT) using Methylene Blue (MB) as the photosensitizing compound and a Light-Emitting Diode (LED) in American cutaneous leishmaniasis (ACL). ...
Propolis reduces Leishmania amazonensis-induced inflammation in the liver of BALB/c mice
Experimental models of mouse paw infection with L. amazonensis show an induction of a strong inflammatory response in the skin, and parasitic migration may occur to secondary organs with consequent tissue injury. There are ...
Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity
(Associação Brasileira de Divulgação Científica, 2007-06-01)
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpß1-3Galpa ...
Effect of phospholipase A2 inhibitors during infection caused by Leishmania (Leishmania) amazonensis
Background: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive ...
Genomic organization of telomeric and subtelomeric sequences of Leishmania (Leishmania) amazonensis
(Pergamon-elsevier Science LtdOxfordInglaterra, 2005)
Natural infection of phlebotomines (Diptera: Psychodidae) by Leishmania (Leishmania) amazonensis in an area of ecotourism in Central-Western Brazil
(BioMed Central, 2015)
Abstract Background Bonito municipality, known as an area of ecoturism, in Mato Grosso do Sul state, Brazil, is also a focus of visceral and cutaneous leishmaniases, with ...
Leishmania amazonensis infection is reduced in macrophages treated with guanine ribonucleosides
(Elsevier Science BvAmsterdamHolanda, 1998)